Identification of genes for otosclerosis and elucidation of their role in the disease process.

The goal of this project is to identify genetic factors that contribute to the development of otosclerosis. Firstly, we will perform linkage analysis and positional cloning in large families with autosomal dominant otosclerosis. Secondly, we will perform a genome wide association study (GWAS) with individual genotyping in a large set of patients and controls.

Keywords:OTOSCLEROSIS, GENES

Disciplines:Genetics, Systems biology, Molecular and cell biology

Project type:Collaboration project