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Laboratory of Endothelial Molecular Biology (VIB-KU Leuven Center for Cancer Biology) KU Leuven

(URL:http://www.kuleuven.be/wieiswie/en/unit/52576632)Laboratory of E ndothelial Molecular Biology (Vesalius Research Center).

The goal of the Laboratory of Endothelial Molecular Biology (VRC) is to expand the current knowledge of how metabolism regulates endothelial redox homeostasis and vice-versa in healthy and diseased conditions. To accomplish this they have taken advantage of the innovative genetic and imaging ...

Physiology University of Antwerp

We study the (patho)physiology of the heart as a muscular pump at the level of clinical medicine, mechanical muscle performance, cellular and molecular biology. A central theme in the laboratory is that the cardiac endothelium modulates the muscular properties of the heart through direct communication with cardiac myocytes. We hypothesize that cardiac endothelial activation/dysfunction is an important pathophysiological aspect of heart failure. ...

Laboratory of Angiogenesis and Vascular Metabolism (VIB-KU Leuven) KU Leuven

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The research group of the Laboratory of Angiogenesis and Neurovascular Link focuses on a central theme, i.e. unraveling the molecular basis of angiogenesis (i.e. the formation of blood vessels) and translating these genetic insights in therapeutic concepts – and, if possible, novel treatments. The group has also broadened its scope of interest to the exciting research avenue of the neurovascular link, illustrating that vessels and nerves have ...

Cell death signaling (CDS) University of Antwerp

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The Cell Death Signaling Lab studies the molecular stress responses which affect cell plasticity (autophagy, transdifferentiation), cell death (apoptosis, necroptosis, ferroptosis, pyroptosis & netosis), or senescence. This research group investigates these mechanisms to improve diagnostic tools or intervention strategies in cell death- or inflammation-driven disease areas. We perform bench-to-bed-oriented research covering biochemistry, ...