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Gert Simonet KU Leuven
Neuropharmacology University of Antwerp
The number of non-neuronal glia cells in the central nervous system exceeds the number of neurons. They all share a strongly branched morphology. Microglia are the immune cells and macrophages of the central nervous system. They comprise about 5 - 20% of the total glia population, and after activation, they display a strongly variable phenotype. Little knowledge is available so far on the biological functions of the different types of glial ...
Lise Verbruggen Vrije Universiteit Brussel
Nathalie De Vocht University of Antwerp
Evelien HOUBEN Hasselt University
Bart De Keersmaecker KU Leuven
Neuro-Aging & Viro-Immunotherapy Vrije Universiteit Brussel
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The ‘Neuro-Aging’ team focuses on glutamate transport, with emphasis on system xc - , in health and disease. We have ongoing projects on the role of system xc - or the cystine/glutamate antiporter in e.g. Parkinson’s disease, Alzheimer’s disease, and (central effects of) (pancreatic) cancer. In most of these projects, neuroimmune communication is receiving increasing attention. Our overall hypothesis that inhibition of system xc - might be a ...