Development and application of filovirus reverse genetics systems for antiviral compound screening KU Leuven
Filoviruses are a rapidly expanding group of human pathogens known for their potential to cause severely debilitating disease with a high mortality rate. Several members of the family Filoviridae can cause filovirus disease but most outbreaks in the last five decades were attributable to the well-known Ebola virus and Marburg virus, the first filovirus to be discovered. Treatment options for Ebola virus disease and Marburg virus disease remain ...