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Substitution treatment for opiate dependent individuals: an international literature review Universiteit Gent
Since the Belgian Federal Drug policy note in 2001, a legal framework has been developed for the prescription and administration of opioid substitution treatment (OST). However, until today policymakers and fieldworkers point at various gaps in the knowledge on substitution treatment in Belgium, in particular regarding substitution treatment in settings outside specialized centres, on the characteristics of clients receiving substitution therapy ...
Analysis and optimization of substitution treatment in Belgium (SUBANOP) Universiteit Gent
Since the Belgian Federal Drug policy note in 2001, a legal framework has been developed for the prescription and administration of opioid substitution treatment (OST). However, until today policymakers and fieldworkers point at various gaps in the knowledge on substitution treatment in Belgium, in particular regarding substitution treatment in settings outside specialized centres, on the characteristics of clients receiving substitution therapy ...
How to overcome hurdles in opiate substitution treatment? Vrije Universiteit Brussel Universiteit Antwerpen
BACKGROUND: Opiate substitution treatment (OST) is the administration of opioids (methadone or buprenorphine) under medical supervision for opiate addiction. Several studies indicate a large unmet need for OST in general practice in Antwerp, Belgium. Some hurdles remain before GPs engage in OST prescribing.
OBJECTIVES: Formulate recommendations to increase engagement of GPs in OST, applicable to Belgium and beyond.
METHODS: In ...
Risk factors of treatment-limiting anemia after substitution of zidovudine for stavudine in HIV-infected adult patients on antiretroviral treatment Instituut voor Tropische Geneeskunde
BACKGROUND: Anemia is the main concern among patients using a zidovudine (AZT)-based antiretroviral treatment (ART). Some studies suggested weight-adjusted AZT dosing as a way to reduce toxicity. We analyzed the risk factors associated with AZT-induced anemia in a cohort using AZT as substitution for stavudine (D4T). METHODS: We retrospectively studied HIV-infected patients in a referral hospital in Phnom Penh, Cambodia between 2003 and 2011. ...
Tuberculosis treatment and risk of stavudine substitution in first-line antiretroviral therapy Universiteit Antwerpen
Background. Treatment for tuberculosis (TB) is common among individuals receiving stavudine-containing highly active antiretroviral therapy (HAART), but the effect of TB treatment on stavudine toxicity has received little attention. We estimated the effect of TB treatment on risk of stavudine substitution among individuals receiving first-line HAART. Methods. We evaluated a cohort of 7066 patients who initiated HAART from April 2004 through ...
Uptake of hepatitis C virus screening and treatment in persons under opioid substitution therapy between 2008 and 2013 in Belgium Universiteit Antwerpen Universiteit Hasselt KU Leuven
Background : Hepatitis C is a viral infection caused by the hepatitis C virus (HCV) with people who inject drugs as the main group at risk worldwide. Aim : This study investigated the differences in uptake for HCV screening and treatment between persons in opioid substitution therapy (OST) and the other members of the Christian Health Insurance Fund in Belgium. Methods : Invoice data were retrospectively collected from the Christian Health ...
Review shows that thyroid hormone substitution could benefit transient hypothyroxinaemia of prematurity but treatment strategies need to be clarified KU Leuven
AIM: Thyroid hormones are crucial for foetal and neonatal brain development. This paper provides an overview of the normal role of thyroid hormones in foetal brain development and the pathophysiology of transient hypothyroxinaemia of prematurity (THOP). It also discusses the diagnostic and therapeutic controversies around THOP and looks at directions for future research. METHODS: We used the PubMed and Embase databases to identify papers ...