Publicaties
Conjugation of milk proteins and reducing sugars and its potential application in the improvement of the heat stability of (recombined) evaporated milk Universiteit Gent
Dynamic voltage stability for embedded electrical networks in marine vessels using FACTS devices Universiteit Gent
Stability of a one-dimensional morphoelastic model for post-burn contraction Universiteit Hasselt
Enhanced intrinsic stability of the bulk heterojunction active layer blend of polymer solar cells by varying the polymer side chain pattern Vrije Universiteit Brussel
Enhanced intrinsic stability of the bulk heterojunction active layer blend of polymer solar cells by varying the polymer side chain pattern Universiteit Hasselt
Low back pain, multifidus muscles, and lumbar stability - an anatomical approach Universiteit Hasselt
MSH2 knock-down shows CTG repeat stability and concomitant upstream demethylation at the DMPK locus in myotonic dystrophy type 1 human embryonic stem cells Instituut voor Tropische Geneeskunde KU Leuven
Myotonic dystrophy type 1 (DM1) is caused by expansion of a CTG repeat in the DMPK gene, where expansion size and somatic mosaicism correlates with disease severity and age of onset. While it is known that the mismatch repair protein MSH2 contributes to the unstable nature of the repeat, its role on other disease-related features, such as CpG methylation upstream of the repeat, is unknown. In this study, we investigated the effect of an MSH2 ...
The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes Instituut voor Tropische Geneeskunde
Various cyclin-dependent kinase (Cdk) complexes have been implicated in the regulation of transcription. In this study, we identified a 70-kDa Cyclin K (CycK) that binds Cdk12 and Cdk13 to form two different complexes (CycK/Cdk12 or CycK/Cdk13) in human cells. The CycK/Cdk12 complex regulates phosphorylation of Ser2 in the C-terminal domain of RNA polymerase II and expression of a small subset of human genes, as revealed in expression ...