Publicaties
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Reversible and size-selective opening of the inner Blood-Retina barrier Vrije Universiteit Brussel
The inner Blood-Retina-barrier (iBRB) remains a key element in retarding the development of novel therapeutics for the treatment of many ocular disorders. The iBRB contains tight-junctions (TJ's) which reduce the space between adjacent endothelial cells lining the fine capillaries of the retinal microvasculature to form a selective and regulatable barrier. We have recently shown that in mice, the iBRB can be transiently and size-selectively ...
Selective liquid filling of photonic crystal fibers using two-photon polymerization lithography without post-exposure development Vrije Universiteit Brussel
Selective liquid filling of photonic crystal fibers opens up possibilities for tailoring their guidance properties or adding new functionalities. Among other techniques, 3D printing on optical fiber tips using two-photon polymerization has been applied for selective infiltration of individual air holes in photonic crystal fibers with liquids. However, in existing techniques care should be taken during the post-print photoresist development in ...
Amidation of Methyl Ester Side Chain bearing Poly(2-oxazoline)s with Tyramine: A Quest for a Selective and Quantitative Approach KU Leuven Universiteit Gent
© 2019 The Royal Society of Chemistry. Poly(2-alkyl/aryl-2-oxazoline)s (PAOx) are a class of cytocompatible polymers that have received growing interest over the past decade. This growing interest can mainly be attributed to their greater chemical versatility compared to other cytocompatible polymers, such as poly(ethylene glycol) (PEG), that originate from the diverse set of monomers compatible with the cationic ring-opening polymerization. ...
Synthesis and biological evaluation of piperazine derivatives as novel isoform selective voltage-gated sodium (Nav) 1.3 channel modulators KU Leuven
© 2014 Springer Science+Business Media New York. Sponges of the genus Agelas produce compounds that modulate the activity of voltage-gated sodium ion channels and contribute novel scaffolds for the development of compounds with activity against a plethora of biological targets. In particular, clathrodin and dibromosceptrin were reported to decrease the average maximum amplitude of inward sodium currents in isolated chick embryo sympathetic ...
Selective dorsal rhizotomy improves muscle forces during walking in children with spastic cerebral palsy KU Leuven
BACKGROUND: Selective dorsal rhizotomy aims to reduce spasticity in children with cerebral palsy. Early investigations indicated postoperative weakness, whereas more recent studies showed that selective dorsal rhizotomy either does not change or improves muscle strength. All previous studies assessed muscle strength in a static position, which did not represent the walking situation. The aim of this study was to analyze the influence of ...
Superior Stability of Au/SiO2 Compared to Au/TiO2 Catalysts for the Selective Hydrogenation of Butadiene KU Leuven
Supported gold nanoparticles are highly selective catalysts for a range of both liquid-phase and gas-phase hydrogenation reactions. However, little is known about their stability during gas-phase catalysis and the influence of the support thereon. We report on the activity, selectivity, and stability of 2-4 nm Au nanoparticulate catalysts, supported on either TiO2 or SiO2, for the hydrogenation of 0.3% butadiene in the presence of 30% propene. ...
Selective suturing or sutureless technique in robot-assisted partial nephrectomy : results from a propensity-score matched analysis Universiteit Gent
Selective and reversible ammonia gas detection with nanoporous film functionalized silicon photonic micro-ring resonator KU Leuven
Portable, low cost and real-time gas sensors have a considerable potential in various biomedical and industrial applications. For such applications, nano-photonic gas sensors based on standard silicon fabrication technology offer attractive opportunities. Deposition of high surface area nano-porous coatings on silicon photonic sensors is a means to achieve selective, highly sensitive and multiplexed gas detection on an optical chip. Here we ...