Publicaties
Gekozen filters:
Gekozen filters:
Gene expression profiling of early hepatic stellate cell activation reveals a role for Igfbp3 in cell migration Vrije Universiteit Brussel KU Leuven
BACKGROUND: Scarring of the liver is the result of prolonged exposure to exogenous or endogenous stimuli. At the onset of fibrosis, quiescent hepatic stellate cells (HSCs) activate and transdifferentiate into matrix producing, myofibroblast-like cells.
AIM AND METHODS: To identify key players during early HSC activation, gene expression profiling was performed on primary mouse HSCs cultured for 4, 16 and 64 hours. Since valproic acid ...
Gene expression profiling of pluripotency and differentiation-related markers in cat oocytes and preimplantation embryos Instituut voor Landbouw-, Visserij- en Voedingsonderzoek Universiteit Gent KU Leuven
During mammalian preimplantation development, two successive differentiation events lead to the establishment of three committed lineages with separate fates: the trophectoderm, the primitive endoderm and the pluripotent epiblast. In the mouse embryo, the molecular mechanisms underlying these two cell fate decisions have been studied extensively, leading to the identification of lineage-specific transcription factors. Species-specific ...
Unifying and targeting cultural activities via events modelling and profiling Universiteit Gent KU Leuven
Embedding functional simulators in compilers for debugging and profiling Universiteit Gent
In embedded systems, achieving good performances for signal processing applications is crucial for power management. Good compilation is required to have maximal use of the available processing capabilities. Compiling for communication-exposed architectures such as ADRES, TRIPS and Wavescalar is however a complex task. Dataflow graphs are mapped on execution unit grids in order to increase the instruction-level parallelism while minimizing ...
Purity profiling and the associated functional effects of a new peptide Universiteit Gent
Peptides show great pharmaceutical potential as active drugs and diagnostics in several clinical areas such as endocrinology, obstetrics or oncology. The search towards novel lead-peptides with a biological function has thus attracted renewed interest. Within a collaborative, multidisciplinary approach investigating the mouse peptidomics [1], new peptides were identified with the potential of serving as a basis towards new peptidic drugs. Tissue ...