Magnetization transfer contrast imaging detects early white matter changes in the APP/PS1 amyloidosis mouse model Universiteit Antwerpen
While no definitive cure for Alzheimer's disease exists yet, currently available treatments would benefit greatly from an earlier diagnosis. It has previously been shown that Magnetization transfer contrast (MTC) imaging is able to detect amyloid beta plaques in old APP/PS1 mice. In the current study we investigated if MTC is also able to visualize early amyloid beta (A beta) induced pathological changes. In a cross-sectional study, a comparison ...