OBJECTIVES: As more has become known of the pathophysiology of osteoarthritis (OA), evidence that inflammation plays a critical role in its development and progression has accumulated. Here, we aim to review current knowledge of the complex inflammatory network in the OA joint. DESIGN: This narrative review is presented in three main sections: local inflammation, systemic inflammation, and therapeutic implications. We focused on inflammatory ...
Increased knee muscle strength is associated with decreased activity limitations in established knee osteoarthritis: Two-year follow-up study in the Amsterdam Osteoarthritis cohort KU Leuven
To examine the association between changes in knee muscle strength (extensor and flexor muscles separately, and mean values) and changes in activity limitations in patients with established knee osteoarthritis at 2 years.
Elevated c-reactive protein is associated with lower increase in knee muscle strength in patients with knee osteoarthritis: a two-year follow up study in the Amsterdam Osteoarthritis (AMS-OA) cohort KU Leuven
The aims of this study were to examine the associations of elevated serum c-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) with change in muscle strength in patients with established knee osteoarthritis (OA), over two years.
Hip movement pathomechanics of patients with hip osteoarthritis aim at reducing hip joint loading on the osteoarthritic side KU Leuven
This study aims at defining gait pathomechanics in patients with hip osteoarthritis (OA) and their effect on hip joint loading by combining analyses of hip kinematics, kinetics and contact forces during gait. Twenty patients with hip OA and 17 healthy volunteers matched for age and BMI performed three-dimensional gait analysis. Hip OA level was evaluated based on plane radiographs using the Tönnis classification. Hip joint kinematics, kinetics ...
Differential proteome analysis of normal and osteoarthritic chondrocytes reveals distortion of vimentin network in osteoarthritis Universiteit Gent
Development of classification criteria for hand osteoarthritis : comparative analyses of persons with and without hand osteoarthritis Universiteit Gent
Responsiveness of Intermittent and Constant Osteoarthritis Pain (ICOAP) after physical therapy for knee osteoarthritis Vrije Universiteit Brussel
The Intermittent and Constant Osteoarthritis Pain (ICOAP)1 questionnaire for the knee (a version for the hip is also available) is a patient-reported pain measure which was developed to assess patients with knee osteoarthritis (OA). Constant and intermittent pain were regarded as relevant by OA patients in a focus group study2. The development of this measure of pain intensity and impact on quality of life was part of a broader Osteoarthritis ...