Publicaties

OBJECTIVES: As more has become known of the pathophysiology of osteoarthritis (OA), evidence that inflammation plays a critical role in its development and progression has accumulated. Here, we aim to review current knowledge of the complex inflammatory network in the OA joint. DESIGN: This narrative review is presented in three main sections: local inflammation, systemic inflammation, and therapeutic implications. We focused on inflammatory ...

To examine the association between changes in knee muscle strength (extensor and flexor muscles separately, and mean values) and changes in activity limitations in patients with established knee osteoarthritis at 2 years.

The aims of this study were to examine the associations of elevated serum c-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) with change in muscle strength in patients with established knee osteoarthritis (OA), over two years.

This study aims at defining gait pathomechanics in patients with hip osteoarthritis (OA) and their effect on hip joint loading by combining analyses of hip kinematics, kinetics and contact forces during gait. Twenty patients with hip OA and 17 healthy volunteers matched for age and BMI performed three-dimensional gait analysis. Hip OA level was evaluated based on plane radiographs using the Tönnis classification. Hip joint kinematics, kinetics ...

The Intermittent and Constant Osteoarthritis Pain (ICOAP)1 questionnaire for the knee (a version for the hip is also available) is a patient-reported pain measure which was developed to assess patients with knee osteoarthritis (OA). Constant and intermittent pain were regarded as relevant by OA patients in a focus group study2. The development of this measure of pain intensity and impact on quality of life was part of a broader Osteoarthritis ...