Publicaties

INTRODUCTION: To systematically review the available literature reporting on genetic mutations leading to dento-maxillofacial malformations in mice. MATERIALS AND METHODS: An electronic search was performed across Embase, PubMed, Web of Science, and Scopus databases up to May 2024, targeting all in vivo studies on gene mutations causing dento-maxillofacial deformities in mice. Studies reporting oral clefts were excluded. Data collected ...

Background The mandibular retromolar space (RMS) has not been extensively studied in relation to various sagittal skeletal classes and patterns of third-molar eruption. The objective of this study was to test the null hypothesis that there is no difference in the mandibular RMS among normodivergent subjects with different skeletal classes and patterns of mandibular third-molar eruption, using cone-beam computed tomography (CBCT). Method A total ...

OBJECTIVES: (1) To investigate the effect of age and diet consistency on maximum lips, tongue and cheek pressure of orthodontically treated and untreated subjects with normal, Class I dental occlusion, (2) to find out whether there is a muscle imbalance between anterior tongue and lip pressure in the same subjects at different ages and (3) to compare the 3D facial shape of treated and untreated individuals. MATERIAL AND METHODS: Subjects with ...

OBJECTIVE: The purpose of this study was to identify an efficient RNA extraction method for periodontal ligament (PDL) and dental pulp (DP) tissues to be used in RNA sequencing studies, given the increased use of these techniques in dental research and the lack of standard protocols. DESIGN: PDL and DP were harvested from extracted third molars. Total RNA was extracted with four RNA extraction kits. RNA concentration, purity and integrity were ...

Methodological bias can directly affect the interpretation of research data. Studies reporting on excavated skeletons represent a valuable source of information in medicine, dentistry, archaeology and anthropology, and forensic sciences. However, these studies represent a specific setting with their own methodology, for which no quality assessment tool is available. The aim was to develop a critical appraisal tool to assess the methodological ...

UNLABELLED: BACKGROUND AND OBJECTIVE(S): (1) To derive descriptive statistics of three-dimensional (3D) facial shape, lip and cheek muscle pressure in subjects of European descent with normal dental occlusion. (2) To analyse the effect of age and sex on 3D-facial soft tissue morphology and muscle pressure in the same sample. (3) To assess the independent effect of muscle pressure on face shape. METHOD: 129 subjects with normal occlusion were ...

OBJECTIVE: To investigate volumetric and circumferential pharyngeal airway space (PAS) changes and stability over time as evaluated with cone beam computed tomography (CBCT) before and after orthognathic surgery 2 years postoperatively. MATERIALS AND METHODS: One hundred twenty-eight patients underwent bimaxillary orthognathic surgery at the Department of Maxillofacial Surgery of University Hospitals, Leuven, Belgium, were recruited ...

OBJECTIVE: The aim of this study was to propose and validate a three-dimensional (3D) methodology for the assessment of canine eruption in patients born with unilateral cleft lip and palate (UCLP) following secondary alveolar bone graft (SABG). METHODS AND MATERIALS: A total of 10 patients (four females, six males; mean age: 8.8 years) with UCLP who underwent SABG were recruited. Pre- and 6-month post-operative cone-beam computed tomography ...

Long-term exposure to occupational noise is often associated with noise-induced hearing loss (NIHL) among dentists. This study aims to investigate potential hearing loss (HL) and selfreported annoyance as a result of exposure to noise produced by contemporary dental equipment. Methods: Three cohorts participated: 53 dentists with more than 5 years of service, 47 dentists with at most 5 years of service, and 53 pharmacists as controls, age and ...