Publicaties
Root-associated bacteria modulate the specialised metabolome of Lithospermum officinale L. Universiteit Gent
Wearable wristband-based electrochemical sensor for the detection of phenylalanine in biofluids Universiteit Antwerpen
Derivatization of amphetamine to allow its electrochemical detection in illicit drug seizures Universiteit Antwerpen
Synthesis and antitubercular activity of 1-and 3-substituted benzo[g]isoquinoline-5,10-diones Universiteit Antwerpen
Synthesis of novel 2-aryl-3-benzoyl-1H-benzo[f]indole-4,9-diones using a domino reaction Universiteit Antwerpen
AhR sensing of bacterial pigments regulates antibacterial defence Universiteit Gent
Biological evaluation of donor-acceptor aminonaphthoquinones as antitumor agents KU Leuven
Preclinical efficacy of sepantronium bromide (YM155) in multiple myeloma is conferred by down regulation of Mcl-1 Vrije Universiteit Brussel
The inhibitor-of-apoptosis family member survivin has been reported to inhibit apoptosis and regulate mitosis and cytokinesis. In multiple myeloma, survivin has been described to be involved in downstream sequelae of various therapeutic agents. We assessed 1093 samples from previously untreated patients, including two independent cohorts of 392 and 701 patients, respectively. Survivin expression was associated with cell proliferation, adverse ...
Temporal changes in Plasmodium falciparum anti-malarial drug sensitivity in vitro and resistance-associated genetic mutations in isolates from Papua New Guinea Instituut voor Tropische Geneeskunde
BACKGROUND: In northern Papua New Guinea (PNG), most Plasmodium falciparum isolates proved resistant to chloroquine (CQ) in vitro between 2005 and 2007, and there was near-fixation of pfcrt K76T, pfdhfr C59R/S108N and pfmdr1 N86Y. To determine whether the subsequent introduction of artemisinin combination therapy (ACT) and reduced CQ-sulphadoxine-pyrimethamine pressure had attenuated parasite drug susceptibility and resistance-associated ...