Publicaties
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Immunohistochemistry using an antibody to unphosphorylated connexin 43 to identify human myometrial interstitial cells KU Leuven
Background: Myometrial smooth myocytes contract as a result of electrical signalling via a process called excitation-contraction coupling. This process is understood in great detail at the cellular level but the generation and coordination of electrical signals throughout the myometrium are incompletely understood. Recent evidence concerning the vital role of interstitial cells of Cajal in tissue-level signalling in gastrointestinal tract, and ...
Transvaginal ultrasound assessment of myometrial and cervical stroma invasion in women with endometrial cancer -interobserver reproducibility among ultrasound experts and gynaecologists KU Leuven
To assess interobserver reproducibility among ultrasound experts and gynaecologists in the prediction of deep myometrial- and cervical stroma invasion by transvaginal ultrasound in women with endometrial cancer.
Transcriptomic analysis reveals the key regulators and molecular mechanisms underlying myometrial activation during equine placentitis Universiteit Gent
The effect of extracellular adenosine triphosphate on the spontaneous contractility of human myometrial strips KU Leuven
OBJECTIVES: Extracellular ATP is involved in cell-cell signalling in a variety of tissues but its effects in tissue level signalling in the myometrium have been poorly studied to date. We hypothesised that extracellular ATP was involved in the control of myometrial contractile frequency and/or force. STUDY DESIGN: In vitro study of the effect of altering the concentration of extracellular ATP on the spontaneous contractility of human myometrial ...
Equine placentitis is associated with a downregulation in myometrial progestin signaling Universiteit Gent
Evaluating myometrial and cervical invasion in women with endometrial cancer - comparing subjective assessment to objective measurement techniques KU Leuven
AIM: To compare the diagnostic accuracy of subjective ultrasound assessment to objective measurement techniques in the evaluation of myometrial and cervical invasion in women with endometrial cancer. METHODS: Prospective multicenter study including 144 women with endometrial cancer undergoing transvaginal ultrasound. Myometrial and cervical invasion was subjectively evaluated, and objectively measured in different ways: ;endometrial thickness, ...
Natural history of pregnancy-related enhanced myometrial vascularity following miscarriage KU Leuven
OBJECTIVES: Our primary aim was to report the incidence of enhanced myometrial vascularity (EMV) in consecutive women attending our early pregnancy assessment unit, following first-trimester miscarriage. We aimed further to evaluate the clinical presentation and complications associated with expectant and surgical management of EMV in these women. METHODS: This was a prospective cohort study conducted in a London teaching hospital between June ...