African trypanosome transmission: unraveling the molecular 'tripartite' between a protozoan parasite, a symbiotic bacterium and the tsetse fly innate immunity Instituut voor Tropische Geneeskunde
Many pathogens including protozoan parasites rely on blood feeding vectors for their transmission. In many cases this is a biological transmission which implies that the parasites have to go through an obligatory developmental cycle within different micro-environments of the vector before dissemination into the mammalian host population can occur. Optimization of a successful parasite transmission is a key evolutionary drive that has influenced ...