Human ccr8 binders Vrije Universiteit Brussel
Qi Lu Hui, Catelijne Stortelers, Nadia Van Boxel, Shanna Van Zwam, Jimmy Borloo, Jo Van Ginderachter, Pascal Merchiers, Rosa Martin
The present invention relates to human CCR8 (hCCR8) binders, wherein the hCCR8 binder is cross-reactive with a non-human primate CCR8. Such binders are particularly useful for the depletion of intra-tumoural regulatory T-cells and immunotherapy in general.