Engineering of cellobiose phosphorylase for glycoside synthesis Universiteit Gent
Glycosylation can significantly influence the properties of a chemical compound. In the case of pharmaceuticals, glycosylation can improve the pharmacokinetic properties of a drug and induce drug targeting to specific organs, resulting in less side effects and smaller required doses. This research is part of a larger project in which the goal is to develop a generic glycosylation technology based on glycoside phosphorylases. Here, the ...