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Nutrient recovery treatment train configuration and optimization using a new model library and global sensitivity analysis Universiteit Gent
Nutrient recovery treatment train set-up using a new model library and global sensitivity analysis Universiteit Gent
Surgical bed stereotactic radiotherapy of brain metastases: Clinical outcome and predictors of local and distant brain failure KU Leuven
PURPOSE: To retrospectively analyze the outcomes of stereotactic radiotherapy (SRT) targeted at surgical bed of brain metastases (BM) and identify patterns of local/distant brain relapses (LR/DBR). PATIENTS/METHODS: Seventy patients were treated with SRT between 2008-2017. Marginal dose prescription on the 70% isodose line depended on the maximal diameter of the target volume and range between 15-18Gy for single fraction radiosurgery and ...
Impaired rich club and increased local connectivity in children with traumatic brain injury : local support for the rich? Universiteit Gent
Glial connexins and pannexins in the healthy and diseased brain Universiteit Gent
Deep brain stimulation of the globus pallidus internus versus the subthalamic nucleus in isolated dystonia KU Leuven
OBJECTIVE: Surgical procedures involving deep brain stimulation (DBS) of the globus pallidus internus (GPi) or subthalamic nucleus (STN) are well-established treatments for isolated dystonia. However, selection of the best stimulation target remains a matter of debate. The authors' objective was to compare the effectiveness of DBS of the GPi and the STN in patients with isolated dystonia. METHODS: In this matched retrospective cohort study, the ...
A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation KU Leuven Vlaams Instituut voor Biotechnologie Universiteit Gent
Hepatic encephalopathy (HE) is a common complication of chronic liver disease, characterized by an altered mental state and hyperammonemia. Insight into the brain pathophysiology of HE is limited due to a paucity of well-characterized HE models beyond the rat bile duct ligation (BDL) model. Here, we assess the presence of HE characteristics in the mouse BDL model. We show that BDL in C57Bl/6j mice induces motor dysfunction, progressive liver ...