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Cardiometabool Risico bij reumatoïde artritis, spondylitis ankylosans en psoriatrische artritis Vrije Universiteit Brussel
Nieuwe ontwikkelingen van een oude aandoening: mastitis onder de loep, deel 2: praktijkgevallen en conclusies Universiteit Gent
Mastitis is an important disease of dairy cattle. The disease has been around for a long time. Still, in the last decades, major changes in the understanding of the epidemiology and pathobiology of the disease have occurred. In this paper, three case studies are discussed, in which a number of these major changes were used to improve the understanding of bovine mastitis in those herds. The results of both the literature review and the case ...
Milk losses linked to mastitis treatments at dairy farms with automatic milking systems Universiteit Gent KU Leuven
Mastitis-associated milk losses in dairy cows have a massive impact on farm profitability and sustainability. In this study, we analyzed milk losses from 4 553 treated mastitis cases as recorded via treatment registers at 41 AMS dairy farms. Milk losses were estimated based on the difference between the expected and the actual production. To estimate the unperturbed lactation curve, we applied an iterative procedure using the Wood model and a ...
Endolysin NC5 improves early cloxacillin treatment in a mouse model of Streptococcus uberis mastitis Universiteit Gent KU Leuven
Streptococcus uberis frequently causes bovine mastitis, an infectious udder disease with significant economic implications for dairy cows. Conventional antibiotics, such as cloxacillin, sometimes have limited success in eliminating S. uberis as a stand-alone therapy. To address this challenge, the study objective was to investigate the VersaTile engineered endolysin NC5 as a supplemental therapy to cloxacillin in a mouse model of bovine S. ...
Invited review : selective treatment of clinical mastitis in dairy cattle Universiteit Gent
Treatment of clinical mastitis (CM) and use of anti-microbials for dry cow therapy are responsible for the majority of animal-defined daily doses of antimicrobial use (AMU) on dairy farms. However, advancements made in the last decade have enabled excluding nonse-vere CM cases from antimicrobial treatment that have a high probability of cure without antimicrobials (no bacterial causes or gram-negative, excluding Klebsiella spp.) and cases with a ...
Nieuwe ontwikkelingen van een oude aandoening: mastitis onder de loep, deel 1: literatuuroverzicht Universiteit Gent
Mastitis is an important disease of dairy cattle. The disease has been around for a long time. Still, in the last decades, major changes in the understanding of the epidemiology and pathobiology of the disease have occurred. In this paper, the major changes in the understanding of bovine mastitis that have taken place in the last decade, are discussed. These major changes include molecular diagnostics, mathematical modeling, immune respons, ...
Providing probability distributions for the causal pathogen of clinical mastitis using naive Bayesian networks Universiteit Gent
Enterobactin deficiency in a coliform mastitis isolate decreases its fitness in a murine model : a preliminary host-pathogen interaction study Universiteit Gent
Iron is an essential nutrient for bacterial growth. Therefore, bacteria have evolved chelation mechanisms to acquire iron for their survival. Enterobactin, a chelator with high affinity for ferric iron, is secreted by Escherichia coli and contributes to its improved bacterial fitness. In this preliminary study, we evaluated enterobactin deficiency both in vitro and in vivo in the context of E. coli mastitis. Firstly, we showed that expression of ...