Observations on the viability of C6-glioma cells after sonoporation with low-intensity ultrasound and microbubbles Universiteit Antwerpen
Ultrasound (US) and microbubbles can be used to facilitate cellular uptake of drugs through a cavitation-induced enhancement of cell membrane permeability. The mechanism is, however, still incompletely understood. A direct contact between microbubbles and cell membrane is thought to be essential to create membrane perturbations lasting from seconds to minutes after US exposure of the cells. A recent study showed that the effect may even last up ...