Publicaties
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Occupancy of the kappa opioid receptor by naltrexone predicts reduction in drinking and craving KU Leuven
The efficacy of naltrexone to treat alcohol use disorder (AUD) is modest. A better understanding of the neurobiology underlying naltrexone effects could optimize treatments. We evaluated the occupancy of the kappa opioid receptor (KOR) by naltrexone measured with [11C]-LY2795050 positron emission tomography (PET) as a predictor of response to naltrexone. Response to naltrexone was defined as the difference in craving and the difference between ...
The Kappa Opioid Receptor Is Associated With Naltrexone-Induced Reduction of Drinking and Craving KU Leuven
BACKGROUND: Naltrexone is a nonselective opioid receptor antagonist used as a treatment for alcohol use disorder. However, only modest clinical effects have been observed, possibly because of limited knowledge about the biological variables affecting the efficacy of naltrexone. We investigated the potential role of the kappa opioid receptor (KOR) in the therapeutic effect of naltrexone. METHODS: A total of 48 non-treatment-seeking heavy drinkers ...
"Arising from Existence and Non-Existence Drawing Inspiration from the Marimba" Vrije Universiteit Brussel
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Definition of the reference point in micro-EDM drilling of a wire drawing die KU Leuven
In micro-EDM milling and drilling, the reference point on the workpiece is usually defined by using the cylindrical tool electrode as the touch probe of a CMM. This method is not only limited in terms of uncertainty of the measurement results, but may also be barely applicable when accessing features processed by other manufacturing techniques. This paper aims to introduce an alternative procedure based on off-machine measurements when the size ...
Case studies of thermally driven heat pump assisted drying Universiteit Gent
Can Youth with Autism Spectrum Disorder Use Virtual Reality Driving Simulation Training to Evaluate and Improve Driving Performance? An Exploratory Study Universiteit Hasselt
Investigate how novice drivers with autism spectrum disorder (ASD) differ from experienced drivers and whether virtual reality driving simulation training (VRDST) improves ASD driving performance. 51 novice ASD drivers (mean age 17.96 years, 78% male) were randomized to routine training (RT) or one of three types of VRDST (8-12 sessions). All participants followed DMV behind-the-wheel training guidelines for earning a driver's license. ...
Driver distraction and in-vehicle interventions: A driving simulator study on visual attention and driving performance Universiteit Hasselt
Driving simulator studies are popular means to investigate driving behaviour in a controlled environment and test safety-critical events that would otherwise not be possible in real-world driving conditions. While several factors affect driving performance, driving distraction has been emphasised as a safety-critical issue across the globe. In this context, this study explores the impact of distraction imposed by mobile phone usage, i.e., ...
Aberrant driving behaviors as mediators in the relationship between driving anger patterns and crashes among taxi drivers: An investigation in a complex cultural context Universiteit Hasselt
Objective: Taxis have become an integrated component of Qatar's urban transportation network due to their convenience, comfort, and flexibility. Qatar has seen an uptick in the demand for professional taxi drivers. Most Qatari taxi drivers come from developing countries with poor awareness of road safety; therefore, they regularly engage in aberrant driving behavior, leading to traffic violations and crashes. For taxi rides to be safer, it is ...