Improving the diagnosis of tuberculosis in hard to diagnose populations : clinical evaluation of GeneXpert MTB/RIF and alternative approaches in Ethiopia Instituut voor Tropische Geneeskunde
Background: The GeneXpert MTB/RIF® assay (Xpert MTB/RIF) was endorsed as the initial diagnostic tool in people suspected of HIV-associated or drug resistant tuberculosis (TB). However, information regarding the performance of Xpert for diagnosing smear-negative TB in high burden settings remains limited. We evaluated the diagnostic accuracy of Xpert MTB/RIF and the impact of bleach-concentration on the performance of Xpert MTB/RIF using ...