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Task matters: Individual MEG signatures from naturalistic and neurophysiological brain states KU Leuven Universiteit Gent
The discovery that human brain connectivity data can be used as a "fingerprint" to identify a given individual from a population, has become a burgeoning research area in the neuroscience field. Recent studies have identified the possibility to extract these brain signatures from the temporal rich dynamics of resting-state magneto encephalography (MEG) recordings. Nevertheless, it is still uncertain to what extent MEG signatures can serve as an ...
Deep brain stimulation for the treatment of Alzheimer's disease: A systematic review and meta-analysis KU Leuven
BACKGROUND: One of the experimental neuromodulation techniques being researched for the treatment of Alzheimer's disease (AD) is deep brain stimulation (DBS). To evaluate the effectiveness of DBS in AD, we performed a systematic review and meta-analysis of the available evidence. METHODS: From the inception through December 2021, the following databases were searched: Medline via PubMed, Scopus, Embase, Cochrane Library, and Web of Science. The ...
Cost-effectiveness of point-of-care interventions to tackle inappropriate prescribing of antibiotics in high- and middle-income countries: A Systematic Review KU Leuven
BACKGROUND: Antimicrobial resistance (AMR) is propagated by widespread inappropriate use of antibiotics. In response, point-of-care interventions (POCIs) have been developed in primary care to preserve antibiotic effectiveness. Many of these POCIs are adopted based on their clinical value. However, assessment of their cost-effectiveness is crucial as well. OBJECTIVES: To summarize the evidence on cost-effectiveness of POCIs aimed at tackling ...
Malnutrition risk and frailty in head and neck cancer patients Vrije Universiteit Brussel
PURPOSE: Both malnutrition and frailty are associated with adverse treatment outcomes. Malnutrition (risk) and frailty are each commonly present in patients with head and neck cancer (HNC). However, their coexistence and association is unknown. Main goal of this study is to determine the coexistence of, and the association between malnutrition risk and frailty in patients with HNC.
METHODS: In this retrospective analysis on ...
netANOVA: novel graph clustering technique with significance assessment via hierarchical ANOVA. KU Leuven
Many problems in life sciences can be brought back to a comparison of graphs. Even though a multitude of such techniques exist, often, these assume prior knowledge about the partitioning or the number of clusters and fail to provide statistical significance of observed between-network heterogeneity. Addressing these issues, we developed an unsupervised workflow to identify groups of graphs from reliable network-based statistics. In particular, ...
Farmers’ preferences for East African highland cooking banana ’Matooke’ hybrids and local cultivars KU Leuven
Background An understanding of farmers’ preferences of new banana cultivars and their characteristics is critical for developing and selecting cultivars that meet consumer needs. Therefore, phenotypic selection in a genetically variable population remains an important aspect of plant breeding. Methods The participatory varietal selection approach for preference ranking was used on 31 ’Matooke’ secondary and primary triploid hybrids and local ...
Large-scale analyses of CAV1 and CAV2 suggest their expression is higher in post-mortem ALS brain tissue and affects survival KU Leuven
Introduction: Caveolin-1 and Caveolin-2 (CAV1 and CAV2) are proteins associated with intercellular neurotrophic signalling. There is converging evidence that CAV1 and CAV2 (CAV1/2) genes have a role in amyotrophic lateral sclerosis (ALS). Disease-associated variants have been identified within CAV1/2 enhancers, which reduce gene expression and lead to disruption of membrane lipid rafts. Methods: Using large ALS whole-genome sequencing and ...
Road marking BRDF model applicable for a wide range of incident illumination conditions KU Leuven
To drive safely and comfortably, an adequate contrast between the road surface and road markings is needed. This contrast can be improved by using optimized road illumination designs and luminaires with dedicated luminous intensity distributions, taking advantage of the (retro)reflective characteristics of the road surface and road markings. Since little is known about road markings' (retro)reflective characteristics for the incident and viewing ...
Comparison of feed tables, empirical models and near-infrared spectroscopy to predict chemical composition and net energy of pelleted pig feeds Instituut voor Landbouw-, Visserij- en Voedingsonderzoek
The determination of the net energy (NE) of a pig feed requires expensive in vivo experiments. Alternatives are available whether the feed ingredient composition is known or unknown. We compared three estimation methods: feed tables, empirical models based on chemical parameters and in vitro digestibility and near-infrared spectroscopy (NIRS) calibrations based on feed and feces spectra. All methods were evaluated for their accuracy in ...