Projecten
Moleculaire en functionele analyse van 2 gloednieuwe vormen van Congenital Disorders of Glycosylatin (CDG). KU Leuven
Met dit onderzoeksproject hebben we de unieke mogelijkheid om de moleculaire mechanismen waarmee Golgi-homeostase wordt onderhouden te onderzoeken en te identificeren hoe de veranderde homeostase van invloed kan zijn op de Golgi-functie en kan leiden tot ziekte..
A role for Presenilin 2/?-secretase in endolysosomal homeostasis of human neurons and microglia: relevance to Alzheimer’s disease Vlaams Instituut voor Biotechnologie
Understanding the molecular biology of membrane transport in a disease-related context covering Alzheimer’s disease and congenital disorders of glycosylation type II.
Unraveling the role of presenilin1 in organellar calcium homeostasis Vlaams Instituut voor Biotechnologie
Understanding the molecular biology of membrane transport in a disease-related context covering Alzheimer’s disease and congenital disorders of glycosylation type II.
On the role of Presenilins in interorganellar communication and Ca2 + handling Vlaams Instituut voor Biotechnologie
Understanding the molecular biology of membrane transport in a disease-related context covering Alzheimer’s disease and congenital disorders of glycosylation type II.
An integrated in vitro and in vivo study to unravel the function of VPS13C, the first genetic risk factor in Lewy Body disease Vlaams Instituut voor Biotechnologie
Understanding the molecular biology of membrane transport in a disease-related context covering Alzheimer’s disease and congenital disorders of glycosylation type II.
Role of ARF6 in PSEN1 mediated endo-lysosomal defects Vlaams Instituut voor Biotechnologie
Understanding the molecular biology of membrane transport in a disease-related context covering Alzheimer’s disease and congenital disorders of glycosylation type II.
Regulation of Presenilin2-mediated intracellular ab accumulation and effects and lysosomal Vlaams Instituut voor Biotechnologie
Understanding the molecular biology of membrane transport in a disease-related context covering Alzheimer’s disease and congenital disorders of glycosylation type II.