Publicaties
Meta-analyses of randomized controlled trials show suboptimal validity of surrogate outcomes for overall survival in advanced colorectal cancer Universiteit Hasselt
Chromosome 8q23.3 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome Vrije Universiteit Brussel
BACKGROUND & AIMS: Recent genome-wide association studies have identified common low-risk variants for colorectal cancer (CRC). To assess whether these influence CRC risk in the Lynch syndrome, we genotyped these variants in a large series of proven mutation carriers.
METHODS: We studied 675 individuals from 127 different families from the Dutch Lynch syndrome Registry whose mutation carrier status was known. We genotyped 8q24.21, ...
Pathologist second opinion significantly alters clinical management of pT1 endoscopically resected colorectal cancer Universiteit Gent
The impact of surgical resection of the primary tumor on the development of synchronous colorectal liver metastasis : a systematic review Universiteit Gent
Metabolic syndrome and colorectal neoplasms : an ominous association Universiteit Gent
Increased MUTYH mutation frequency among Dutch families with breast cancer and colorectal cancer Vrije Universiteit Brussel
Homozygous and compound heterozygous MUTYH mutations predispose for MUTYH-associated polyposis (MAP). The clinical phenotype of MAP is characterised by the multiple colorectal adenomas and colorectal carcinoma. We previously found that female MAP patients may also have an increased risk for breast cancer. Yet, the involvement of MUTYH mutations in families with both breast cancer and colorectal cancer is unclear. Here, we have genotyped the ...
The role of the peritoneal microenvironment in the pathogenesis of colorectal peritoneal carcinomatosis Universiteit Gent
Transmuscular quadratus lumborum (TQL) block for laparoscopic colorectal surgery: study protocol for a double-blind, prospective randomized placebo-controlled trial Universiteit Hasselt KU Leuven
Does elevated intra-abdominal pressure during laparoscopic colorectal surgery cause acute gastrointestinal injury? Vrije Universiteit Brussel
INTRODUCTION: The incidence of acute gastrointestinal injury (AGI) after colorectal surgery is low when laparoscopic techniques are used. While elevated intra-abdominal pressure (IAP) and intra-abdominal hypertension (IAH) are associated with AGI grade II, little is known about the relation between increased IAP during laparoscopy and subsequent AGI.
AIM: To assess the impact of increased IAP during laparoscopic colorectal surgery on ...