Projecten
Endothelial Cell Molecular and Metabolic Heterogeneity in Pulmonary Arterial Hypertension — EMPAtHy (Marie curie individual felloxship voor Sebastien Dumas) Vlaams Instituut voor Biotechnologie
The molecular basis of conductive and vascular tissue development in plants Vlaams Instituut voor Biotechnologie
Understanding the molecular mechanisms controlling the orientation of plant cell divisions Vlaams Instituut voor Biotechnologie
Targeting bicarbonate transport as a “first-in-class” therapeutic strategy to promote CD8+ T cell fitness and enhance cancer immunotherapy Vlaams Instituut voor Biotechnologie
Endothelial immunosuppressive mystery genes for alternative immunotherapy: artificial intelligence-driven target discovery and lipid nanoparticle/RNA-based target validation. Vlaams Instituut voor Biotechnologie
MiCrovasculaR rarefaction in vascUlar Cognitive Impairement and heArt faiLure’ — ‘CRUCIAL’ Vlaams Instituut voor Biotechnologie
Peroxisoom interacties en communicatie KU Leuven
PERICO fosters education of ESRs in a project to uncover how a central metabolic organelle, the peroxisome, participates in controlling cellular metabolism. It trains 15 ESRs at world-leading academic institutions, including university hospitals, and companies, thus forming strong interdisciplinary links between industry, life and medical sciences, and end-users.
PERICO aims to train a new generation of highly qualified ESRs with ...
Diepe eencellige fenotypering om de leidende principes en mechanismen van de subcellulaire organisatie van bacteriële replicatie te identificeren KU Leuven
Modern metagenomics has opened our eyes to the immense bacterial diversity that exists both among and within us. Despite this diversity, all bacteria share the basic challenge of organizing the various processes that ensure their faithful replication. All bacterial cells need to metabolize nutrients, generate building blocks, maintain their shape and size, replicate and segregate their chromosomes, synthesize cell walls and membranes, and ...
HeMiBio - Hepatic Microfluidic Bioreactor. KU Leuven
The goal of HeMiBio is to develop a hepatic microfluidic bioreactor from human iPSC-derived hepatocytes, hepatic sinusoidal endothelial cells (HSEC) and stellate cells (HSC), suitable for inclusion in a repeated dose toxicity testing strategy of pharmaceuticals/cosmetic ingredients. The succesful creation of such a liver-device requires (a) homotypic and heterotypic interactions between the three cell types to induce and maintain their ...