Balancing between immunity and tolerance: interplay between dendritic cells, effector T cells and regulatory T cells Universiteit Antwerpen
Functionally mature CD4 and CD8 TCRU+03B1U+03B2 cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells Universiteit Gent
Long-term culture and differentiation of porcine red bone marrow hematopoietic cells co-cultured with immortalized mesenchymal cells Universiteit Gent
Equine herpesvirus type 1 enhances viral replication in CD172aU+207A monocytic cells upon adhesion to endothelial cells Universiteit Gent
Human induced pluripotent stem cells differentiate into insulin-producing cells able to engraft in vivo Vrije Universiteit Brussel
AIMS: New sources of insulin-secreting cells are strongly required for the cure of diabetes. Recent successes in differentiating embryonic stem cells, in combination with the discovery that it is possible to derive human induced pluripotent stem cells (iPSCs) from somatic cells, have raised the possibility that patient-specific beta cells might be derived from patients through cell reprogramming and differentiation. In this study, we aimed to ...
Double-negative T resident memory cells of the lung react to influenza virus infection via CD11chi dendritic cells Universiteit Gent
T-lymphoid differentiation potential measured in vitro is higher in CD34+CD38-/lo hematopoietic stem cells from umbilical cord blood than from bone marrow and is an intrinsic property of the cells Universiteit Gent
Crosstalk between glial and glioblastoma cells triggers the "go-or-grow" phenotype of tumor cells KU Leuven
V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A Synthetic Modified mRNA Drives Reprogramming of Human Pancreatic Duct-Derived Cells Into Insulin-Secreting Cells Vrije Universiteit Brussel
: β-Cell replacement therapy represents the most promising approach to restore β-cell mass and glucose homeostasis in patients with type 1 diabetes. Safety and ethical issues associated with pluripotent stem cells stimulated the search for adult progenitor cells with endocrine differentiation capacities. We have already described a model for expansion and differentiation of human pancreatic duct-derived cells (HDDCs) into insulin-producing ...