Glucose-geinduceerde cel signalen in ß cellen van de pancreas: mechanismes voor adaptatie en implicaties voor zwangerschapsdiabetes.
Ontdekken en preklinische validering van myeloide cel signalen als nieuwe doelwitten en biomerkers voor de ontwikkeling van fibrose in IBD
The combination of inhibitors of FGF/MEK/Erk and GSK3U+03B2 signaling increases the number of OCT3/4-and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation
Combined Notch and PDGF Signaling Enhances Migration and Expression of Stem Cell Markers while Inducing Perivascular Cell Features in Muscle Satellite Cells
Polyfunctional tumor antigen-specific T cells generated in vitro from human CD34 positive precursor cells transduced to express T cell receptor alpha beta chains fused to CD28-CD3 zeta signaling cassette
PME-1 sensitizes glioblastoma cells to oxidative stress-induced cell death by attenuating PP2A-B55α-mediated inactivation of MAPKAPK2-RIPK1 signaling
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
SCREENING FOR COMPOUNDS THAT MODULATE GPR3-MEDIATED BETA-ARRESTIN SIGNALING AND AMYLOID BETA PEPTIDE GENERATION
Imaging the invisible in preclinical models using magnetic particle imaging (MPI Magnetic Particle Imaging)
Ultrafast tandem ICP mass spectrometer for interference-free and high-sensitivity monitoring of transient signals (ICP-MS/MS)
A multimodal non-linear optical platform for 2l3-photon excitation and 2ndl3rd harmonic imaging deep inside living tissues and animals (Multimodal NLO imaging platform)
Replication Data for: Cell signaling and tissue remodeling in the pulmonary autograft after the Ross procedure: a computational study
Replication Data for: Loss of INPP5K attenuates agonist-induced Ca2+ responses in the glioblastoma cell line U-251 MG cells
Replication Data for: Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells