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A new generation of AD biomarkers : 2019 to 2021 Universiteit Gent

Jade Hawksworth, Esperanza Fernández, Kris Gevaert
Alzheimer's disease (AD) is the most common form of dementia and cases are rising worldwide. The effort to fight this disease is hampered by a lack of disease-modifying treatments and the absence of an early, accurate diagnostic tool. Neuropathology begins years or decades before symptoms occur and, upon onset of symptoms, diagnosis can take a year or more. Such delays postpone treatment and make research into the early stages of the disease ...

Does supplementation with leucine-enriched protein alone and in combination with fish-oil-derived n-3 PUFA affect muscle mass, strength, physical performance, and muscle protein synthesis in well-nourished older adults? Vrije Universiteit Brussel

Caoileann H Murphy, Ellen M Flanagan, Giuseppe De Vito, Davide Susta, Kathleen A J Mitchelson, Elena de Marco Castro, Joan M G Senden, Joy P B Goessens, Agnieszka Mikłosz, Adrian Chabowski, et al.

BACKGROUND: Leucine-enriched protein (LEU-PRO) and long-chain (LC) n-3 (ω-3) PUFAs have each been proposed to improve muscle mass and function in older adults, whereas their combination may be more effective than either alone.

OBJECTIVE: The impact of LEU-PRO supplementation alone and combined with LC n-3 PUFAs on appendicular lean mass, strength, physical performance and myofibrillar protein synthesis (MyoPS) was investigated in ...

A semi-automated method for unbiased alveolar morphometry: validation in a bronchopulmonary dysplasia model Instituut voor Tropische Geneeskunde KU Leuven

Thomas Salaets, Bieke Tack, Andre Gie, Benjamin Pavie, Nikhil Sindhwani, Julio Jimenez, Yannick Regin, Karel Allegaert, Jan Deprest, Jaan Toelen, et al.

Reproducible and unbiased methods to quantify alveolar structure are important for research on many lung diseases. However, manually estimating alveolar structure through stereology is time consuming and inter-observer variability is high. The objective of this work was to develop and validate a fast, reproducible and accurate (semi-)automatic alternative. A FIJI-macro was designed that automatically segments lung images to binary masks, and ...

Body & brain project : experience report of the pilot intervention Universiteit Gent

Elizaveta Fomenko, Arnaldina Sampaio, Flavia Machado, Duarte Barros, Maria Santos, Joana Carvalho
BACKGROUND: Dementia is one of the main age-related health problems affecting society nowadays (World Health Organization, 2017). This fact is concerning several institutions like the European Commission that recognizes and alerts countries for the need to develop and implement national intervention plans against Dementia (Rosow et al., 2011). In addition, evidence has shown that physical exercise is capable of increasing brain flow and ...

Public support and advocacy success across the legislative process Universiteit Antwerpen

Evelien Willems, Jan Beyers
This paper examines how public support affects interest groups’ advocacy success across three distinct stages in the legislative process. We hypothesize that public support is vital for advocacy success when coalition agreements are negotiated, and it has a weaker effect when legislation is introduced in parliament by the governing majority but becomes stronger again when legislation is adopted. We assess these expectations for 55 Belgian policy ...

Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic KU Leuven

Wouter Oosterlinck, Anna Kisiel, Troy Munro
BACKGROUND: This study aimed to determine the impact of pulmonary complications on death after surgery both before and during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. METHODS: This was a patient-level, comparative analysis of two, international prospective cohort studies: one before the pandemic (January-October 2019) and the second during the SARS-CoV-2 pandemic (local emergence of COVID-19 up to 19 April ...

The ESC-EORP EURO-ENDO (European Infective Endocarditis) registry Vrije Universiteit Brussel

Gilbert Habib, Patrizio Lancellotti, Paola Anna Erba, Anita Sadeghpour, Marwa Meshaal, Antonia Sambola, Shumaila Furnaz, Rodolfo Citro, Julien Ternacle
Aims The European Society of Cardiology (ESC) EURObservational Research Programme (EORP) European Endocarditis (EURO-ENDO) registry aims to study the care and outcomes of patients diagnosed with infective endocarditis (IE) and compare findings with recommendations from the 2015 ESC Clinical Practice Guidelines for the management of IE and data from the 2001 Euro Heart Survey.

Methods and results Patients (n = 3116) aged over 18 years ...

Behind success stories: goal attainment in global trade and climate negotiations Universiteit Antwerpen

Kirsten Lucas
How successful are transnational advocates? If they are successful, is this due to their advocacy efforts or because of a favourable policy context? This paper examines the policy success of transnational advocates. In doing so, it focuses on the positions interest groups adopt, the strategies they develop, and how these interact with the context of specific policy issues. Based on 467 interviews with non-state actors who were involved in 17 ...

Lobbying strategies and success: inside and outside lobbying in European Union legislative politics Universiteit Antwerpen

Iskander De Bruycker, Jan Beyers
In their pursuit of political influence, interest groups face the choice to contact policy elites directly or to generate pressure indirectly by appealing to the public at large. This article examines whether interest groups should prioritize inside or outside lobbying tactics in order to materialize their policy objectives, with a specific focus on European Union legislative policymaking. This article demonstrates that outside lobbying is not ...