Publicaties
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A long-term prospective cohort study on immediately restored single tooth implants inserted in extraction sockets and healed ridges : CBCT analyses, soft tissue alterations, aesthetic ratings, and patient-reported outcomes Universiteit Gent Vrije Universiteit Brussel
Background: Although many studies have been published on single implants, long-term data remain scarce. Purpose: To evaluate immediately restored single implants after at least 8 years of follow-up in terms of buccal bone, soft tissue alterations, aesthetic ratings, and patient-reported outcomes. Materials and Methods: This prospective cohort study included patients who were consecutively treated with an immediately restored single implant ...
Melanoma with genetic alterations beyond the BRAFV600 mutation Vrije Universiteit Brussel
PURPOSE OF REVIEW: Molecular-targeted therapy with BRAF-/MEK-inhibitors has shown impressive activity in patients with advanced BRAFV600 mutant melanoma. In this review, we aim to summarize recent data and possible future therapeutic strategies involving small-molecule molecular-targeted therapies for advanced BRAFV600 wild-type melanoma.
RECENT FINDINGS: In patients with NRASQ61 mutant melanoma, downstream MEK-inhibition has shown ...
Segmental chromosomal alterations lead to a higher risk of relapse in infants with MYCN-non-amplified localised unresectable/disseminated neuroblastoma (a SIOPEN collaborative study) Universiteit Gent
BACKGROUND: In neuroblastoma (NB), the presence of segmental chromosome alterations (SCAs) is associated with a higher risk of relapse. METHODS: In order to analyse the role of SCAs in infants with localised unresectable/disseminated NB without MYCN amplification, we have performed an array CGH analysis of tumours from infants enroled in the prospective European INES trials. RESULTS: Tumour samples from 218 out of 300 enroled patients could be ...
Is traumatic and non-traumatic neck pain associated with brain alterations? : a systematic review Universiteit Gent Universiteit Antwerpen
Study of genomic alterations in colon carcinoma by array comparative genomic hybridization Universiteit Gent
Oncogene alterations in endometrial carcinosarcomas Universiteit Gent
Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project Universiteit Gent
Alterations of the ionic composition in different organs of spotted murrel (Channa punctatus) exposed to sublethal concentration of endosulfan Universiteit Gent
Behavioural alterations relevant to developmental brain disorders in mice with neonatally induced ventral hippocampal lesions KU Leuven
Neonatal lesioning of the ventral hippocampus (vHc) in rats has served as a useful heuristic animal model to elucidate neurodevelopmental mechanisms of schizophrenia (SCZ). In the current study we have established that this procedure can be applied to model SCZ symptomatology in mice. Neonatal mice (postnatal day 6) were anaesthetised by hypothermia and electrolytic lesions of the vHc were induced. We observed locomotor hyperactivity at ...