Publicaties
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Dissociations between ABA-, ABC-, and AAB-renewal of Pavlovian modulation in human sequential Feature Positive discrimination learning KU Leuven
Using a conditioned suppression preparation, we investigated extinction and aba-, abc-, and aab-renewal of Pavlovian modulation in human sequential Feature Positive (FP) discrimination learning, X → A+/A-. Extinction treatment was administered in the acquisition context a (aaa- and aab-groups) or in a new context b (aba- and abc-groups) and comprised X → A- extinction trials. Discriminative X → A/A responding was lost in all groups when tested ...
The ABC's of Alzheimer risk gene ABCA7. Vlaams Instituut voor Biotechnologie
The abc of ABCD: the reference manual Universiteit Antwerpen
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio. Vrije Universiteit Brussel
The amyloid peptides Ab40 and Ab42 of Alzheimer's disease are thought to contribute differentially to the disease process. Although Ab42 seems more pathogenic than Ab40, the reason for this is not well understood. We show here that small alterations in the Ab42:Ab40 ratio dramatically affect the biophysical and biological properties of the Ab mixtures reflected in their aggregation kinetics, the morphology of the resulting amyloid fibrils and ...
Targeted AntiBiotics for Chronic pulmonary diseases (TARGET ABC) Universiteit Antwerpen
Background: Pseudomonas aeruginosa infection is seen in chronic pulmonary disease and is associated with exacerbations and poor long-term prognosis. However, evidence-based guidelines for the management and treatment of P. aeruginosa infection in chronic, non-cystic fibrosis (CF) pulmonary disease are lacking. The aim of this study is to investigate whether targeted antibiotic treatment against P. aeruginosa can reduce exacerbations and ...
ABCA transporter gene expression and poor outcome in epithelial ovarian cancer KU Leuven
ATP-binding cassette (ABC) transporters play various roles in cancer biology and drug resistance, but their association with outcomes in serous epithelial ovarian cancer (EOC) is unknown.
Sanac Inc. : from ABC to time-driven ABC : an instructional case Universiteit Gent
Upregulation of ABC transporters contributes to chemoresistance of sphingosine 1-phosphate lyase-deficient fibroblasts KU Leuven
Sphingosine 1-phosphate (S1P) is an extra- and intracellular mediator that regulates cell growth, survival, migration, and adhesion in many cell types. S1P lyase is the enzyme that irreversibly cleaves S1P and thereby constitutes the ultimate step in sphingolipid catabolism. It has been reported previously that embryonic fibroblasts from S1P lyase-deficient mice (Sgpl1(-/-)-MEFs) are resistant to chemotherapy-induced apoptosis through ...
Assessment of the postoperative effect of corneal cross-linking on keratoconus using the ABCD grading system Vrije Universiteit Brussel
PURPOSE: To monitor the changes in the ABCD grading system during a one-year follow-up after a corneal cross-linking (CXL) procedure.
METHODS: This prospective study included 30 eyes of 25 patients with keratoconus, who received the CXL treatment. The patients with a history of ocular trauma or surgery and other corneal pathology were excluded from the study. The patients were examined at the baseline visit and followed up at 3, 6, ...