A proof-of-concept trial to evaluate artesunate-mefloquine as a novel alternative treatment for schistosomiasis in African children Instituut voor Tropische Geneeskunde
Departement Klinische Wetenschappen, Beheer, Malariologie, Clinical Trials Unit, Medische Helminthologie, Tropische Geneeskunde
Schistosomiasis is a major Neglected Tropical Disease in sub-Saharan Africa, disproportionally affecting children living in poor rural areas. For decades, both treatment and control of schistosomiasis have relied on a single drug, praziquantel (PZQ). Given its massive use in current mass drug administration campaigns, emergence of praziquantel resistance is a threat, and finding alternative treatments against schistosomiasis is an urgent ...