Publicaties
Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis KU Leuven
Validation assessment of risk tools to predict outcome after thrombolytic therapy for acute ischemic stroke Vrije Universiteit Brussel Universiteit Antwerpen
Methods: In a cohort of 169 patients, 60 patients (35.5%) received IV rtPA according to the European license criteria. The remaining patients received off-label IV rtPA and/or were treated with ...
Changes in Activated Thrombin-Activatable Fibrinolysis Inhibitor Levels Following Thrombolytic Therapy in Ischemic Stroke Patients Correlate with Clinical Outcome Vrije Universiteit Brussel
BACKGROUND AND PURPOSE: Thrombin-activatable fibrinolysis inhibitor (TAFI) activation following thrombolysis may affect thrombolysis effectiveness in acute ischemic stroke (AIS). To support this hypothesis, we propose to study the relationship between TAFI consumption, activated/inactivated TAFI (TAFIa/ai) and stroke severity and outcome in 2 groups of AIS patients, one treated and one untreated with intravenous recombinant tissue type ...
Thrombolytics in acute ischaemic stroke: historical perspective and future opportunities KU Leuven
Microbubbles in ultrasound-triggered drug and gene delivery Vrije Universiteit Brussel
Flushing and Locking of Venous Catheters: Available Evidence and Evidence Deficit KU Leuven
Urokinase-containing locking solution in the prevention of dialysis catheter dysfunction: a double blind randomized controlled trial Vrije Universiteit Brussel Universiteit Gent Universiteit Antwerpen
Introduction: The prophylactic use of recombinant tissue plasminogen activator once weekly reduces the incidence rate of tunneled cuffed catheter (TCC) malfunction and bacteremia as compared to the exclusive use of heparin as locking solution. Restricting the use of prophylactic thrombolytic agents to patients with a history of thrombotic TCC malfunction could be more cost effective. We conduct a multicenter, double-blind, randomized ...
Safety and Outcome of Revascularization Treatment in Patients With Acute Ischemic Stroke and COVID-19 Vrije Universiteit Brussel KU Leuven
BACKGROUND AND OBJECTIVES: COVID-19-related inflammation, endothelial dysfunction, and coagulopathy may increase the bleeding risk and lower the efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate the safety and outcomes of revascularization treatments in patients with AIS and COVID-19.
METHODS: This was a retrospective multicenter cohort study of consecutive patients with AIS ...