Publicaties
Six weeks of strength endurance training decreases circulating senescence-prone T-lymphocytes in cytomegalovirus seropositive but not seronegative older women Vrije Universiteit Brussel
Background: Ageing is associated with a decline in immune function termed immunosenescence. This process is characterized amongst others by less naive T-cells and more senescent phenotypes, which have been implicated in the pathogenesis of many age-related diseases. Thus far, reports regarding the long-term adaptation effects of exercise on T-cell phenotypes are scant and largely equivocal. These inconsistencies may be due to potential ...
The relative biological effectiveness of a high energy neutron beam for micronuclei induction in T-lymphocytes of different individuals Universiteit Gent
Proliferation capacity of T-lymphocytes is affected transiently after a long-term weight gain in Beagle dogs KU Leuven
Cellular aging and senescence characteristics of human T-lymphocytes. Vrije Universiteit Brussel
Aging-associated subpopulations of human CD8+ T-lymphocytes identified by their CD28 and CD57 phenotypes Vrije Universiteit Brussel
BACKGROUND: During organismal aging, human T-cells shift towards less functional phenotypes, often called senescent cells. As these cells have not been well characterized, we aimed to relate surface markers of human T-cell senescence with characteristics of in vitro cellular aging and to further characterize these cells.
METHODS: We identified, by flow cytometry, subpopulations of CD8+ T-cells based on CD57 and CD28 expression, and ...