Publicaties
Serologic tests for sleeping sickness: importance of antigen selection Instituut voor Tropische Geneeskunde
Combining antibody tests and taking into account antibody levels improves serologic diagnosis of celiac disease KU Leuven
The diagnostic accuracy of serological tests for Lyme borreliosis in Europe: a systematic review and meta-analysis Instituut voor Tropische Geneeskunde
BACKGROUND: Interpretation of serological assays in Lyme borreliosis requires an understanding of the clinical indications and the limitations of the currently available tests. We therefore systematically reviewed the accuracy of serological tests for the diagnosis of Lyme borreliosis in Europe.
METHODS: We searched EMBASE en MEDLINE and contacted experts. Studies evaluating the diagnostic accuracy of serological assays for Lyme ...
Diagnostic Performance of Seven Commercial COVID-19 Serology Tests Available in South America Instituut voor Tropische Geneeskunde
BACKGROUND: Although RT-qPCR remains the gold-standard for COVID-19 diagnosis, anti-SARS-CoV-2 serology-based assays have been widely used during 2020 as an alternative for individual and mass testing, and are currently used for seroprevalence studies.
OBJECTIVE: To study the clinical performance of seven commercial serological tests for COVID-19 diagnosis available in South America.
METHODS: We conducted a blind evaluation of ...
Bayesian estimation of the prevalence and test characteristics (sensitivity and specificity) of two serological tests (RB and SAT-EDTA) for the diagnosis of bovine brucellosis in small and medium cattle holders in Ecuador Instituut voor Tropische Geneeskunde
In Ecuador, a national program for bovine brucellosis control has been in implementation since 2008. Given the costs, small- and medium-sized livestock holders are not completely committed to it. The objective of this study was to determine true prevalence (TP) of bovine brucellosis in small- and medium-sized herd populations, as well as the diagnostic sensitivity and specificity of the Rose Bengal (RB) test and the sero-agglutination test ...
Urologic, neurologic, and general practice implications of the Time to be Ready to Void test Universiteit Gent
Chronic and Early Antiretroviral Therapy Impact Human Immunodeficiency Virus (HIV) Serological Assay Sensitivity, Leading to More False-Negative Test Results in HIV Diagnosis Vrije Universiteit Brussel KU Leuven Universiteit Gent Instituut voor Tropische Geneeskunde
This retrospective study evaluated the reactivity of 3 human immunodeficiency virus (HIV) confirmatory assays (INNO-LIA, Geenius, and MP) and 7 HIV rapid tests on samples from 2 different study populations in Belgium. For the early-treated cohort (83 HIV-1 adult patients treated within 3 months after infection), HIV-1 diagnosis was not obtained in at least 1 confirmatory assay in 12.0% (10/83) and in an HIV rapid test in 31.3% (26/83). ...