HOSTE, Julien Judith, hoogleraar analytische scheikunde, expert in de radiochemie, rector en vicerector van de Universiteit Gent Universiteit Antwerpen
A4 Scheikunde KU Leuven
Analytical techniques for metabolomic studies Vrije Universiteit Brussel
Metabolomics is the comprehensive study of small-molecule metabolites. Obtaining a wide coverage of the metabolome is challenging because of the broad range of physicochemical properties of the small molecules. To study the compounds of interest spectroscopic (NMR), spectrometric (MS) and separation techniques (LC, GC, supercritical fluid chromatography, CE) are used. The choice for a given technique is influenced by the sample matrix, the ...
Targeted Isolation of Monoterpene Indole Alkaloids from Palicourea sessilis. Vrije Universiteit Brussel
Aqueous size-exclusion chromatographic separations of intact proteins under native conditions: Effect of pressure on selectivity and efficiency Vrije Universiteit Brussel
New tetracyclic tetrahydro-beta-carbolines as tryptophan-derived peptidomimetics Vrije Universiteit Brussel
HPLC analysis of polyphenols in the fruits of Rubus idaeus L. (Rosaceae) Vrije Universiteit Brussel
Bioactive Azepine-Indole Alkaloids from Psychotria nemorosa Vrije Universiteit Brussel
Phytochemical investigation of the alkaloid extract of the aerial parts of Psychotria nemorosa led to the isolation and characterization of 10 azepine-indole alkaloids, i.e., cimitrypazepine (1), fargesine (2), nemorosines A (3), and B (12), nemorosinosides A-F (4-9), as well as two β-carboline derivatives, 10-hydroxyisodolichantoside (10) and 10-hydroxydolichantoside (11), an isoxazole alkaloid, nemorosinoside G (13), serotonin (14), ...
All that glitters is not gold: Panning cytotoxic natural products and derivatives with a fused tricyclic backbone by the estimation of their leadlikeness for cancer treatment. Vrije Universiteit Brussel
natural products (NPs) are a prodigal source of polycyclic compounds, comprising classes, such as carbolines, anthraquinones and ...