Publicaties
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Method validation to assess in vivo cellular and subcellular changes in buccal mucosa cells and saliva following CBCT examination Universiteit Hasselt KU Leuven
OBJECTIVES:: Cone-beam CT (CBCT) is a medical imaging technique used in dental medicine. However, there are no conclusive data available indicating that exposure to X-ray doses used by CBCT are harmless. We aim, for the first time, to characterize the potential age-dependent cellular and subcellular effects related to exposure to CBCT imaging. Current objective is to describe and validate the protocol for characterization of cellular and ...
Circulating cell-free DNA in health and disease : the relationship to health behaviours, ageing phenotypes and metabolomics Universiteit Gent Vlaams Instituut voor Biotechnologie
Report on EFSA project GP/EFSA/AFSCO/2017/03 “Detection and Quantification of Allergens in Foods and Minimum Eliciting Doses in Food-Allergic Individuals” (ThRAll) Instituut voor Landbouw-, Visserij- en Voedingsonderzoek
Mandatory labelling of allergenic food ingredients has helped allergic consumer manage their condition, but unintended allergensand precautionary allergen labels (PAL) continue to cause confusion for allergic consumers and the food industryalike. Identifying doses of food protein that are safe for the majority of allergic consumersand test methods for their analysis are essential for evidence-basedapplication of allergen ...
First Report of ‘ Candidatus Phytoplasma solani’ Infecting Plum ( Prunus domestica ) in Jordan Instituut voor Landbouw-, Visserij- en Voedingsonderzoek
Plum (Prunus domestica L., Rosaceae) is among the most important stone fruit species grown in Jordan, especially in the northeastern part of the country. In September 2017, 30 trees from a 2-ha orchard of cultivar ‘Early Queen’ showing possible phytoplasma symptoms of leaf yellowing and reddening, stunted growth, and witches’ broom were observed. Additionally, there were around 20 bindweed plants (Convolvulus arvensis L.) among the plum trees ...
European Association of Urology Guidelines on Male Sexual and Reproductive Health: 2021 Update on Male Infertility KU Leuven
CONTEXT: The European Association of Urology (EAU) has updated its guidelines on sexual and reproductive health for 2021. OBJECTIVE: To present a summary of the 2021 version of the EAU guidelines on sexual and reproductive health, including advances and areas of controversy in male infertility. EVIDENCE ACQUISITION: The panel performed a comprehensive literature review of novel data up to January 2021. The guidelines were updated and a strength ...
cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing KU Leuven
Inappropriate stimulation or defective negative regulation of the type I interferon response can lead to autoinflammation. In genetically uncharacterized cases of the type I interferonopathy Aicardi-Goutières syndrome, we identified biallelic mutations in LSM11 and RNU7-1, which encode components of the replication-dependent histone pre-mRNA-processing complex. Mutations were associated with the misprocessing of canonical histone transcripts and ...
First report of brown rot on peach, nectarine, cherry and plum fruits caused by Monilinia fructicola in Bulgaria Instituut voor Landbouw-, Visserij- en Voedingsonderzoek
Field surveys in the region of Plovdiv within a small mixed orchard of peach and nectarine trees in the summer of 2017 revealed symptoms and signs of brown rot attended by numerous, slightly greyish conidial pustules on the surface of unripe and mature fruits. Similar symptoms and signs were found also in the summer of 2018 on cherry and plum fruits in two additional orchards in the same region. The putative Monilinia species (Ogawa et al. 1995) ...
Supporting Spartina Universiteit Antwerpen
In 2014, a DNA-based phylogenetic study confirming the paraphyly of the grass subtribe Sporobolinae proposed the creation of a large monophyletic genus Sporobolus, including (among others) species previously included in the genera Spartina, Calamovilfa, and Sporobolus. Spartina species have contributed substantially (and continue contributing) to our knowledge in multiple disciplines, including ecology, evolutionary biology, molecular biology, ...
Neoadjuvant degarelix with or without apalutamide followed by radical prostatectomy for intermediate and high-risk prostate cancer: ARNEO, a randomized, double blind, placebo-controlled trial KU Leuven
BACKGROUND: Recent retrospective data suggest that neoadjuvant androgen deprivation therapy can improve the prognosis of high-risk prostate cancer (PCa) patients. Novel androgen receptor pathway inhibitors are nowadays available for treatment of metastatic PCa and these compounds are promising for early stage disease. Apalutamide is a pure androgen antagonist with a very high affinity with the androgen receptor. The combination of apalutamide ...