Publicaties
Genomic analysis of Salmonella enterica serotype Paratyphi A during an outbreak in Cambodia, 2013-2015 Instituut voor Tropische Geneeskunde KU Leuven Universiteit Antwerpen
In 2013, an unusual increase in the number of Salmonella enterica serotype Paratyphi A (Salmonella Paratyphi A) infections was reported in patients in Phnom Penh, Cambodia, and in European, American and Japanese travellers returning from Cambodia. Epidemiological investigations did not identify a common source of exposure. To analyse the population structure and genetic diversity of these Salmonella Paratyphi A isolates, we used whole-genome ...
Chromogenic media for the detection of Salmonella enterica serovar Paratyphi A in human stool samples: evaluation in a reference setting Instituut voor Tropische Geneeskunde KU Leuven
Detection of Salmonella Paratyphi A stool carriers by conventional stool culture media is hindered by the absence of hydrogen sulphide production compared to most other Salmonella serovars. This study evaluated the detection of Salmonella Paratyphi A in stool samples using Salmonella chromogenic media compared to a conventional medium. Four chromogenic media, COMPASS Salmonella agar (Biokar Diagnostics, Beauvais, France), BBL™ CHROMagar™ ...
Increase in Salmonella enterica serovar Paratyphi A infections in Phnom Penh, Cambodia, January 2011 to August 2013 Universiteit Antwerpen
Development of a real-time PCR method for the genoserotyping of Salmonella Paratyphi B variant Java Universiteit Gent
Case report: visceral leishmaniasis with Salmonella paratyphi and Brucella melitensis coinfection as a cause of persistent fever in a patient from Sudan Instituut voor Tropische Geneeskunde KU Leuven
We describe the case of a 12-year-old boy from Sudan who presented with fever of 1-week duration, headache, cough, and vomiting. A set of diagnostic tests led to the diagnosis of three infectious diseases: visceral leishmaniasis (probable diagnosis based on positive direct agglutination test), enteric fever (blood culture grown with Salmonella Paratyphi), and brucellosis (blood culture grown with Brucella melitensis). The patient received ...
Increase in Salmonella enterica serovar paratyphi A infections in Phnom Penh, Cambodia, January 2011 to August 2013 Instituut voor Tropische Geneeskunde
Salmonella Typhi, Paratyphi A, Enteritidis and Typhimurium core proteomes reveal differentially expressed proteins linked to the cell surface and pathogenicity Universiteit Gent KU Leuven Instituut voor Tropische Geneeskunde Vlaams Instituut voor Biotechnologie Universiteit Antwerpen
Phylogenomic investigation of an outbreak of fluoroquinolone- resistant Salmonella enterica subsp. enterica serovar Paratyphi A in Phnom Penh, Cambodia KU Leuven Instituut voor Tropische Geneeskunde
The clinical and microbiological characteristics of enteric fever in Cambodia, 2008-2015 Instituut voor Tropische Geneeskunde KU Leuven Universiteit Antwerpen
BACKGROUND: Enteric fever remains a major public health problem in low resource settings and antibiotic resistance is increasing. In Asia, an increasing proportion of infections is caused by Salmonella enterica serovar Paratyphi A, which for a long time was assumed to cause a milder clinical syndrome compared to Salmonella enterica serovar Typhi.
METHODOLOGY: A retrospective chart review study was conducted of 254 unique cases of ...