Full Genome-Based Classification of Rotaviruses Reveals Common Origin between Human Wa-like and Porcine rotavirus strains and Human DS-1-like and Bovine Rotavirus strains KU Leuven
Group A rotavirus classification is currently based on the molecular properties of the two outer layer proteins, VP7 and VP4, and the middle layer protein, VP6. As reassortment of all the 11 rotavirus gene segments plays a key role in generating rotavirus diversity in nature, a classification system that is based on all the rotavirus gene segments is desirable for determining which genes influence rotavirus host range restriction, replication ...