Publicaties
Gekozen filters:
Gekozen filters:
Prediction of breast and prostate cancer risks in male BRCA1 and BRCA2 mutation carriers using polygenic risk scores Universiteit Gent
SCORE2 risk prediction algorithms : new models to estimate 10-year risk of cardiovascular disease in Europe Universiteit Gent Universiteit Hasselt
Aims The aim of this study was to develop, validate, and illustrate an updated prediction model (SCORE2) to estimate 10-year fatal and non-fatal cardiovascular disease (CVD) risk in individuals without previous CVD or diabetes aged 40-69 years in Europe. Methods and results We derived risk prediction models using individual-participant data from 45 cohorts in 13 countries (677 684 individuals, 30 121 CVD events). We used sex-specific and ...
SCORE2-OP risk prediction algorithms : estimating incident cardiovascular event risk in older persons in four geographical risk regions Universiteit Gent
The utility of absolute risk prediction using FRAX (R) and Garvan Fracture Risk Calculator in daily practice Universiteit Hasselt
Objectives: There are two commonly used fracture risk prediction tools FRAX® and Garvan Fracture Risk Calculator (GARVAN-FRC). The objective of this study was to investigate the utility of these tools in daily practice. Study design: A prospective population-based 5-year follow-up study was conducted in ten general practice centres in the Netherlands. For the analyses, the FRAX® and GARVAN-FRC 10-year absolute risks (FRAX® does not have 5-year ...
Estimation of the cardiovascular risk using world health organization/international society of hypertension risk prediction charts in Central Vietnam Universiteit Gent Vrije Universiteit Brussel
Introduction Cardiovascular disease (CVD) being the leading cause of the morbidity and mortality in Vietnam, the objective of this study was to estimate the total 10-year CVD risk among adults aged 40-69 years by utilizing World Health Organization/International Society of Hypertension (WHO/ISH) risk prediction charts in Central Vietnam. Materials and methods In this cross-sectional study, multi-staged sampling was used to select 938 ...
Prediction in a risk analysis context: Implications for selecting a risk perspective in practical applications KU Leuven Universiteit Antwerpen
© 2017 Elsevier Ltd Recently, there have been several calls for increased attention to foundational issues in risk analysis, addressing issues like terminology, principles and theories. An important foundational issue is the appropriateness of different concepts and perspectives for analyzing risk in practical applications. Several authors have addressed this through arguments involving, inter alia, the definition of risk, the ontology of risk, ...
Polygenic risk modeling for prediction of epithelial ovarian cancer risk Universiteit Gent Vlaams Instituut voor Biotechnologie KU Leuven
Validation of a new mortality risk prediction model for people 65 years and older in northwest Russia: The Crystal risk score KU Leuven
Prediction models help to make decisions about further management in clinical practice. This study aims to develop a mortality risk score based on previously identified risk predictors and to perform internal and external validations.
A comparison between an ultrasound based prediction model (LR2) and the Risk of Ovarian Malignancy Algorithm (ROMA) to assess the risk of malignancy in women with an adnexal mass KU Leuven
OBJECTIVE: The identification of novel biomarkers led to the development of the ROMA algorithm incorporating both HE4 and CA125 to predict malignancy in women with a pelvic mass. An ultrasound based prediction model (LR2) developed by the International Ovarian Tumor Analysis (IOTA) study offers better diagnostic performance than CA125 alone. In this study we compared the diagnostic accuracy between LR2 and ROMA. METHODS: This study included ...