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A self-learning Digital Twin for Process Control of fast processes under Uncertainty KU Leuven
With the recent developments of sensor technologies appear new opportunities for conducting increasingly efficient and close control of industrial processes. This paper proposes a new scheme for near real-time process control of extremely fast complex processes using the framework of digital twins and an adaptively calibrating grey-box model. It focuses specifically on processes for which first-principle based numerical simulation is ...
Development of process analytical and control methodologies for pharmaceutical wet granulation processes Universiteit Gent
Multivariate statistical process control of a continuous pharmaceutical twin-screw granulation and fluid bed drying process Universiteit Gent
PAT-based batch statistical process control of a manufacturing process for a pharmaceutical ointment Universiteit Gent
Development of a fluid bed granulation process control strategy based on real-time process and product measurements Universiteit Gent
Batch statistical process control of a fluid bed granulation process using in-line spatial filter velocimetry and product temperature measurements Universiteit Gent
How does a resilient, flexible ammonia process look? Robust design optimization of a Haber-Bosch process with optimal dynamic control powered by wind Vrije Universiteit Brussel
Ammonia can be an essential energy vector for storing excess renewable energy during the year and release this energy when demand is high. This storage during the year provides an essential part in the energy sector for moments when there is not enough wind and sun to cover the demand. Although the Haber-Bosch is a very mature process to synthesize hydrogen and nitrogen to ammonia, it is not flexible enough to match the erratic nature of ...
Development of a fluid bed granulation process control strategy based on real-time process and product measurements Vrije Universiteit Brussel
This article describes the results of three case studies conducted consecutively, in order to develop a process control strategy for a top-spray fluid bed granulation process. The use of several real-time particle size (i.e., spatial filter velocimetry and focused beam reflectance measurement) and moisture (i.e., near infrared (NIR) and Lighthouse near infrared spectroscopy) analyzers was examined. A feed-forward process control method was ...