Biomarkers and donor selection in heart transplantation Universiteit Antwerpen KU Leuven
CSF Aβ1-42 - an excellent but complicated Alzheimer's biomarker - a route to standardisation Vrije Universiteit Brussel
The 42 amino acid form of amyloid β (Aβ1-42) in cerebrospinal fluid (CSF) has been widely accepted as a central biomarker for Alzheimer's disease. Several immunoassays for CSF Aβ1-42 are commercially available, but can suffer from between laboratory and batch-to-batch variability as well as lack of standardisation across assays. As a consequence, no general cut-off values have been established for a specific context of use (e.g., clinical ...
Prediction models and peptide profiling in the assessment of the implant ation potential of early embryos KU Leuven
Novel Antibody Targets in Spinal Cord Injury: Study of their Biomarker Potential and Biological Relevance Universiteit Hasselt
Translational Pharmacodynamics of Calcitonin Gene-Related Peptide Monoclonal Antibody LY2951742 in a Capsaicin-Induced Dermal Blood Flow Model KU Leuven
Characterizing the PK/PD relationship for inhibition of capsaicin-induced dermal vasodilatation by MK-3207, an oral calcitonin gene related peptide receptor antagonist KU Leuven
Refining wet lab experiments with in silico searches: A rational quest for diagnostic peptides in visceral leishmaniasis Vrije Universiteit Brussel Universiteit Antwerpen
BACKGROUND: The search for diagnostic biomarkers has been profiting from a growing number of high quality sequenced genomes and freely available bioinformatic tools. These can be combined with wet lab experiments for a rational search. Improved, point-of-care diagnostic tests for visceral leishmaniasis (VL), early case detection and surveillance are required. Previous investigations demonstrated the potential of IgG1 as a biomarker for ...