Proconvulsive effects of oxytocin in the generalized pentylenetetrazol mouse model are mediated by vasopressin 1a receptors Vrije Universiteit Brussel
The possible involvement of oxytocin (OT) in the generation of seizures has not received a
lot of attention in the past, although generalized epileptic convulsions were observed in
humans following intravenous OT infusion. We here aimed to investigate the effect of
exogenous OT administration on seizure susceptibility in C57Bl/6 mice subjected to the
pentylenetetrazol (PTZ) model. In addition, we studied via which receptor ...
lot of attention in the past, although generalized epileptic convulsions were observed in
humans following intravenous OT infusion. We here aimed to investigate the effect of
exogenous OT administration on seizure susceptibility in C57Bl/6 mice subjected to the
pentylenetetrazol (PTZ) model. In addition, we studied via which receptor ...