Multi-component nanodeeltjes als bimodale contrastmiddelen voor MRI en optische detectie van tumoren en voor gerichte fotodynamische therapie KU Leuven
The main aim of this proposal is to synthesize a range of lanthanide containing nanoparticles with an upconverting core, that can be excited in the infrared region to yield emission in the visible range, as for MRI and optical imaging. The nanoparticles will be covered with a rare earth doped MRI active shell and decorated with targeting moieties, which offers a means of targeting cancer cells that greatly over express the receptors. Further ...