Publicaties
The effect of posture-induced changes in peripheral nitric oxide uptake on exhaled nitric oxide Vrije Universiteit Brussel
Abstract
Verbanck S, Kerckx Y, Schuermans D, de Bisschop C, Guenard H, Naeije R, Vincken W, Van Muylem A. The effect of posture-induced changes in peripheral nitric oxide uptake on exhaled nitric oxide. J Appl Physiol 106: 1494-1498, 2009. First published March 19, 2009; doi:10.1152/japplphysiol.91641.2008.-Airway and alveolar NO contributions to exhaled NO are being extracted from exhaled NO measurements performed at different flow ...
Verbanck S, Kerckx Y, Schuermans D, de Bisschop C, Guenard H, Naeije R, Vincken W, Van Muylem A. The effect of posture-induced changes in peripheral nitric oxide uptake on exhaled nitric oxide. J Appl Physiol 106: 1494-1498, 2009. First published March 19, 2009; doi:10.1152/japplphysiol.91641.2008.-Airway and alveolar NO contributions to exhaled NO are being extracted from exhaled NO measurements performed at different flow ...
The nitric oxide suppressed Arabidopsis mutants-Atnoa1 and Atnia1nia2noa1-2 produce nitric oxide in MS growth medium and on uranium exposure Universiteit Hasselt
The mutants Atnoa1 and Atnia1nia2noa1-2 having a defective chloroplast developmental process, showed enhanced chlorophyll levels when they were grown on Murashige and Skoog (MS) medium and on exposure with uranium (U) on Hoagland medium. Thus we hypothesized that these mutants probably produced NO in MS medium and on exposure with U. Wild-type Col-0, Atnoa1, Atnia1nia2noa1-2 plants were cultured on modified Hoagland and 1/10 MS media and NO ...
Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with asthma: a systematic review and individual patient data meta-analysis KU Leuven
BACKGROUND: High exhaled nitric oxide fraction (F ENO) levels are associated with greater risk of asthma exacerbation. However, it is not clear how F ENO can be used to guide safe reductions in inhaled corticosteroid (ICS) doses in asthma patients. This study assesses the ability of F ENO to guide ICS reductions. METHODS: Systematic searching of electronic databases identified prospective observational studies and randomised controlled trials ...
The nitric oxide dependence of cutaneous microvascular function to independent and combined hypoxic cold exposure Vrije Universiteit Brussel
Hypoxic modulation of nitric oxide (NO) production pathways in the cutaneous microvasculature and its interaction with cold-induced reflex vasoconstriction, independent of local cooling, have yet to be identified. This study assessed the contribution of NO to nonglabrous microvasculature perfusion during hypoxia and whole body cooling with concomitant inhibition of NO synthase [NOS; via NG-nitro-l-arginine methyl ester (l-NAME)] and the ...
No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers Vrije Universiteit Brussel KU Leuven
OBJECTIVES: To assess whether migraine patients display a chronic nitric oxide synthase (NOS) hyperactivity by comparing the nitric oxide (NO) production before and following a loading dose of L-arginine between migraine patients (interictally) and matched healthy control subjects. In addition, we evaluated whether a loading dose of L-arginine triggers an acute migraine headache in migraineurs.
SUBJECTS AND METHODS: Twenty healthy ...
Circulating biomarkers of nitric oxide bioactivity and impaired muscle vasoreactivity to exercise in adults with uncomplicated type 1 diabetes Vrije Universiteit Brussel
AIMS/HYPOTHESIS: Early compromised endothelial function challenges the ability of individuals with type 1 diabetes to perform normal physical exercise. The exact mechanisms underlying this vascular limitation remain unknown, but may involve either formation or metabolism of nitric oxide (NO), a major vasodilator, whose activity is known to be compromised by oxidative stress.
METHODS: Muscle microvascular reactivity (near-infrared ...
Sulfide- and nitrite-dependent nitric oxide production in the intestinal tract Universiteit Gent
In the gut ecosystem, nitric oxide (NO) has been described to have damaging effects on the energy metabolism of colonocytes. Described mechanisms of NO production are microbial reduction of nitrate via nitrite to NO and conversion of l-arginine by NO synthase. The aim of this study was to investigate whether dietary compounds can stimulate the production of NO by representative cultures of the human intestinal microbiota and whether this ...
Process-driven bacterial community dynamics are key to cured meat colour formation by coagulase-negative staphylococci via nitrate reductase or nitric oxide synthase activities Vrije Universiteit Brussel
The cured colour of European raw fermented meats is usually achieved by nitrate-into-nitrite reduction by coagulase-negative staphylococci (CNS), subsequently generating nitric oxide to form the relatively stable nitrosomyoglobin pigment. The present study aimed at comparing this classical curing procedure, based on nitrate reductase activity, with a potential alternative colour formation mechanism, based on nitric oxide synthase (NOS) activity, ...