Publicaties
HIV-1 candidate vaccines can induce antibodies which share specificity with human monoclonal antibodies capable of neutralizing primary isolates Instituut voor Tropische Geneeskunde
Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques Instituut voor Tropische Geneeskunde Universiteit Antwerpen
Definition of antibody (Ab) functions capable of preventing mucosal HIV transmission may be critical to both effective vaccine development and the prophylactic use of monoclonal Abs. Although direct antibody-mediated neutralization is highly effective against cell-free virus, increasing evidence suggests an important role for immunoglobulin G (IgG) Fcγ receptor (FcγR)-mediated inhibition of HIV replication. Thus, a panel of well-known ...
Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals Instituut voor Tropische Geneeskunde
Neutralizing antibodies in HIV-infected or HIV-vaccinated individuals Instituut voor Tropische Geneeskunde
Sequential vaccinations with divergent H1N1 influenza virus strains induce multi-H1 clade neutralizing antibodies in swine Universiteit Gent
HPV-specific antibodies in female genital tract secretions captured via first-void urine retain their neutralizing capacity. Universiteit Antwerpen
In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C cirus Universiteit Antwerpen Universiteit Gent
A novel competition ELISA for the rapid quantification of SARS-CoV-2 neutralizing antibodies in convalescent plasma Universiteit Gent
Apolipoprotein E mediates evasion from hepatitis C virus neutralizing antibodies Instituut voor Tropische Geneeskunde Universiteit Gent
BACKGROUND & AIMS: Efforts to develop an effective vaccine against hepatitis C virus (HCV) have been hindered by the propensity of the virus to evade host immune responses. HCV particles in serum and in cell culture associate with lipoproteins, which contribute to viral entry. Lipoprotein association has also been proposed to mediate viral evasion of the humoral immune response, though the mechanisms are poorly defined.
METHODS: ...