Inhibition of a lncRNA for treatment of neuroblastoma Universiteit Gent
The present invention relates to the field of cancer, particularly to the treatment of neuroblastoma. Indeed, the present invention discloses that a particular long non-coding RNA (lncRNA) is specifically upregulated in neuroblastoma cells as compared to other cancer cells and that high expression of said lncRNA correlates with a lower survival probability. Inhibition of this lncRNA in neuroblastoma cells leads to a reduction in cell growth and induction of apoptosis and is a novel therapeutic strategy in the treatment of neuroblastoma.