Publicaties
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A near-infrared spectroscopy study on thermal transitions of PMMA and PMMA/SiO2 nanocomposites Universiteit Gent
Lower Extremity Near-infrared Spectroscopy After Popliteal Block For Orthopaedic Foot Surgery Vrije Universiteit Brussel Universiteit Gent KU Leuven
BACKGROUND: Noninvasive measurement of cutaneous tissue oxygenation using near-infrared spectroscopy (NIRS) has become common in peri-operative care. Following institution of peripheral nerve blocks, neurovascular alterations in the blocked region have been described.
OBJECTIVE: The primary aim of this study encompassed the assessment of the influence of a popliteal block on changes in regional oxygen saturation (SrO2), and the ...
Use of near-infrared spectroscopy in the neonatal intensive care unit KU Leuven
Near-infrared spectroscopy was first described in 1977 as a non-invasive technique to measure the cerebral oxygenation and cytochrome oxydase. Different techniques have been developed resulting in new instruments that make it possible to measure cerebral oxygenation in a non-invasive way. In this chapter the physiology and pathophysiology in relation to the measurement of cerebral oxygenation are explained and the direct possible clinical use ...
Do Cerebral Cortex Perfusion, Oxygen Delivery, and Oxygen Saturation Responses Measured by Near-Infrared Spectroscopy Differ Between Patients Who Fail or Succeed in a Spontaneous Breathing Trial? A Prospective Observational Study KU Leuven
BACKGROUND: Alterations in perfusion to the brain during the transition from mechanical ventilation (MV) to a spontaneous breathing trial (SBT) remain poorly understood. The aim of the study was to determine whether changes in cerebral cortex perfusion, oxygen delivery (DO2), and oxygen saturation (%StiO2) during the transition from MV to an SBT differ between patients who succeed or fail an SBT. METHODS: This was a single-center prospective ...
Localization of cortical response to audiovisual, visual, and auditory speech stimuli using functional near-infrared spectroscopy : an exploratory study in normal-hearing adults Universiteit Gent
Background: Functional near-infrared spectroscopy (fNIRS) is an increasingly popular technique used to investigate cortical function, including auditory- and visual- functions. fNIRS provides a silent and non-invasive functional imaging technique that is compatible with hearing devices. However, fNIRS is only recently adopted in auditory research (Harrison et al., 2021) and considerable variability exists in the experimental designs and analysis ...
Microvascular reactivity monitored with near-infrared spectroscopy is impaired after induction of anaesthesia in cardiac surgery patients An observational study KU Leuven Universiteit Gent
BACKGROUND: Induction of anaesthesia causes significant macrohaemodynamic changes, but little is known about its effects on the microcirculation. However, alterations in microvascular perfusion are known to be associated with impaired tissue oxygenation and organ dysfunction. Microvascular reactivity can be assessed with vascular occlusion testing, which evaluates the response of tissue oxygen saturation to transient ischaemia and reperfusion. ...
Application of near-infrared spectroscopy for the classification of fresh pork quality in cooked ham production KU Leuven Universiteit Gent
Destructured zones in the core of cooked ham are associated with PSE in terms of biochemical characteristics. In this study, the potential of near-infrared spectroscopy (NIRS) to predict the suitability of fresh pork for the production of cooked ham was investigated. Using NIR spectra obtained in a first trial (inducing PSE characteristics in Longissimus thoracis et lumborum (LTL) muscles) and in a second trial (collecting Semimembranosus (SM) ...
An observational near-infrared spectroscopy study on cerebral autoregulation in post-cardiac arrest patients: time to drop 'one-size-fits-all' hemodynamic targets? Universiteit Hasselt KU Leuven
AIMS: A subgroup of patients with ROSC after cardiac arrest (CA) with disturbed cerebral autoregulation might benefit from higher mean arterial pressures (MAP). We aimed to (1) phenotype patients with disturbed autoregulation, (2) investigate whether these patients have a worse prognosis, (3) define an individual optimal MAP per patient and (4) investigate whether time under this individual optimal MAP is associated with outcome. METHODS: ...
Development of a near-infrared Raman spectroscopy setup compatible with fluorescence-guided surgery Universiteit Antwerpen
Near-infrared (NIR) fluorescence imaging using exogenous fluorescent agents provides whole-field images in real-time to assist the surgeon in the excision of a tumor. Although the method has high sensitivity, the specificity can sometimes be lower than expected. Raman spectroscopy can detect tumors with high specificity. Therefore, a combination of both techniques can be advantageous. A complication that must be addressed is that the NIR ...