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Multiplex Analysis of Cerebrospinal Fluid and Serum Exosomes MicroRNAs of Untreated Relapsing Remitting Multiple Sclerosis (RRMS) and Proposing Noninvasive Diagnostic Biomarkers Universiteit Hasselt
Exosomal microRNAs (miRNAs) are emerging diagnostic biomarkers for neurodegenerative diseases. In this study, we aimed to detect relapsing-remitting multiple sclerosis (RRMS)-specific miRNAs in cerebrospinal fluid (CSF) and serum exosomes with diagnostic potential. One ml of CSF and serum sample were collected from each of the 30 untreated RRMS patients and healthy controls (HCs). A panel of 18 miRNAs affecting inflammatory responses was ...
Multiplexed superconducting qubit control at millikelvin temperatures with a low-power cryo-CMOS multiplexer Interuniversitair Micro-Electronica Centrum vzw
Diagnostic characterization of respiratory allergies by means of a multiplex immunoassay Universiteit Hasselt
Allergic sensitization is commonly assessed in patients by performing the skin prick test (SPT) or determining specific immunoglobulin (IgE) levels in blood samples with the ImmunoCAP (TM) assay, which measures each allergen and sample separately. This paper explores the possibility to investigate respiratory allergies with a high throughput method, the Meso Scale Discovery (MSD) multiplex immunoassay, measuring IgE levels in low volumes of ...
Bringing the multiplex to Antwerp Universiteit Antwerpen
This article investigates the introduction of the first multiplex in Antwerp, Belgium. Within Europe, Belgium has traditionally been a leader in multiplex developments. Despite Antwerp’s powerful position in terms of national film exhibition and distribution, the city’s first multiplex arrived relatively late. By investigating the struggles of two major exhibitors in the late 1980s and early 1990s, this case of Antwerp connects to findings for ...
Covering the combinatorial design space of multiplex CRISPR/Cas experiments in plants Universiteit Gent Instituut voor Landbouw-, Visserij- en Voedingsonderzoek
Over the past years, CRISPR/Cas-mediated genome editing has revolutionized plant genetic studies and crop breeding. Specifically, due to its ability to simultaneously target multiple genes, the multiplex CRISPR/Cas system has emerged as a powerful technology for functional analysis of genetic pathways. As such, it holds great potential for application in plant systems to discover genetic interactions and to improve polygenic agronomic traits in ...
Rapid diagnostic multiplex PCR (RD-PCR) to discriminate Schistosoma haematobium and S. bovis KU Leuven
Schistosoma haematobium and S. bovis are widespread schistosome species causing human and cattle schistosomiasis, respectively, in Africa. The sympatric occurrence of these two species and their ability to infect the same Bulinus intermediate snail hosts necessitates precise methods of identification of the larval stages. A rapid diagnostic 'mulitplex' one-step polymerase chain reaction protocol (RD-PCR) was developed using cytochrome oxidase ...