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Impact of multimodality therapy in esophageal cancer on disease, patient and treatment KU Leuven

Lieven Depypere
Multimodality treatment in potentially curable locally advanced esophageal cancer (EC) and cancer of the gastro-esophageal junction (GEJC) is standard practice in most patients because it is improving local control and survival in the majority of patients. We hypothesize that multimodality treatment in these patients is not always synonym of improved outcome compared to primary surgery on one hand, but on the other hand, multimodality treatment ...

Multimodality imaging in the diagnosis, risk stratification, and management of patients with dilated cardiomyopathies Vrije Universiteit Brussel

Erwan Donal, Victoria Delgado, Chiara Bucciarelli-Ducci, Elena Galli, Kristina H Haugaa, Philippe Charron, Jens-Uwe Voigt, Nuno Cardim, P G Masci, Maurizio Galderisi, et al.

Dilated cardiomyopathy (DCM) is defined by the presence of left ventricular or biventricular dilatation and systolic dysfunction in the absence of abnormal loading conditions or coronary artery disease sufficient to explain these changes. This is a heterogeneous disease frequently having a genetic background. Imaging is important for the diagnosis, the prognostic assessment and for guiding therapy. A multimodality imaging approach provides a ...

Multimodality imaging in takotsubo syndrome Vrije Universiteit Brussel

Rodolfo Citro, Hiroyuki Okura, Jelena R Ghadri, Chisato Izumi, Patrick Meimoun, Masaki Izumo, Dana Dawson, Shuichiro Kaji, Ingo Eitel, Nobuyuki Kagiyama, et al.

Takotsubo syndrome (TTS) is a complex and still poorly recognized heart disease with a wide spectrum of possible clinical presentations. Despite its reversibility, it is associated with serious adverse in-hospital events and high complication rates during follow-up. Multimodality imaging is helpful for establishing the diagnosis, guiding therapy, and stratifying prognosis of TTS patients in both the acute and post-acute phase. ...

Imaging the adult with congenital heart disease: a multimodality imaging approach-position paper from the EACVI KU Leuven

Giovanni Di Salvo, Owen Miller, Sonya Babu Narayan, Wei Li, Werner Budts, Emanuela R Valsangiacomo Buechel, Alessandra Frigiola, Annemien E van den Bosch, Beatrice Bonello, Luc Mertens, et al.
Advances in the diagnosis and management of congenital heart disease have led to a marked improvement in the survival of adult with congenital heart disease (ACHD) patients. However, ACHD patients are a heterogeneous population, with a large spectrum of anatomic substrates even within specific lesions. In addition, the nature of previous surgery and other intervention is highly variable rendering each patient unique and residual anatomic and ...

Serial Multimodality Imaging and 2-Year Clinical Outcomes of the Novel DESolve Novolimus-Eluting Bioresorbable Coronary Scaffold System for the Treatment of Single De Novo Coronary Lesions Vrije Universiteit Brussel

Alexandre Abizaid, Ricardo A. Costa, Joachim Schofer, John Ormiston, Michael Maeng, Bernhard Witzenbichler, Roberto V. Botelho, J., Jr. Ribamar Costa, Daniel Chamie, Andrea S. Abizaid, et al.
OBJECTIVES This study sought to report the late multimodality imaging and clinical outcomes of the novel poly-L-lactic-acid-based DESolve novolimus-eluting bioresorbable coronary scaffold for the treatment of de novo coronary lesions.

BACKGROUND Bioresorbable scaffolds are an alternative to drug-eluting metallic stents and provide temporary vascular scaffolding, which potentially may allow vessel restoration and reduce the risk of ...

Role of multimodality cardiac imaging in the management of patients with hypertrophic cardiomyopathy: an expert consensus of the European Association of Cardiovascular Imaging Endorsed by the Saudi Heart Association Vrije Universiteit Brussel

Nuno Cardim, Maurizio Galderisi, Thor Edvardsen, Sven Plein, Bogdan A. Popescu, Antonello D'Andrea, Oliver Bruder, Bernard Cosyns, Laurent Davin, Erwan Donal, et al.
Taking into account the complexity and limitations of clinical assessment in hypertrophic cardiomyopathy (HCM), imaging techniques play an essential role in the evaluation of patients with this disease. Thus, in HCM patients, imaging provides solutions for most clinical needs, from diagnosis to prognosis and risk stratification, from anatomical and functional assessment to ischaemia detection, from metabolic evaluation to monitoring of treatment ...

Anatomical Markov Prior-based Multimodality Image Registration KU Leuven

Kathleen Vunckx, Frederik Maes, Johan Nuyts
Some similarity measures used in state-of-the-art multimodality image registration algorithms, (e.g., mutual information (MI)) have been shown to be suitable anatomical priors for maximum a posteriori reconstruction in emission tomography. Therefore, it is reasonable to assume that some originally designed anatomical priors may also be well suited for multimodality image registration. In this work, we evaluate the registration performance of ...

Transcatheter aortic valve implantation: role of multimodality cardiac imaging Vrije Universiteit Brussel

Victoria Delgado, Arnold Ng, Miriam Shanks, Frank Van Der Kley, Joanne Schuijf, Lucia Kroft, Albert De Roos, Martin Schalij, Jeroen Bax, Nico Van De Veire, et al.
Current evidence based on more than 8000 high-risk patients with severe aortic stenosis has demonstrated that transcatheter aortic valve implantation (TAVI) is a feasible alternative to surgical aortic valve replacement in selected patients. Despite current promising results on hemodynamic and clinical improvements, there are several unresolved safety issues, such as the frequency of vascular complications, postprocedural paravalvular leak, ...

Cardiac myxoma: a contemporary multimodality imaging review KU Leuven

Geoffrey C Colin, Bernhard L Gerber, Mihaela Amzulescu, Jan Bogaert
Cardiac myxoma (CM) is by far the most common primary benign cardiac tumor, typically arising in the left atrium with an attachment point in the fossa ovalis region. Although the etiology of CM remains unclear, we know that this endocardial-based mass originates from undifferentiated mesenchymal cells. Continuous technical improvements in the field of echocardiography since the 1960s has profoundly changed the diagnostic approach by allowing a ...