Projecten
Epidemiological study and molecular characterization of no-tsetse transmitted trypanosomes in Ethiopia: understanding the importance of mechanical versus cyclical transmission in control strategies. Instituut voor Tropische Geneeskunde
Simplified rapid molecular diagnosis and characterisation of Leishmaniasis and Human African Trypanosomiasis Instituut voor Tropische Geneeskunde
General
To generate new knowledge and technologies for improved diagnosis and control of human African trypanosomiasis and leishmaniasis.
Specific
To develop and validate low-tech molecular tests for laboratory diagnosis and (sub-)species differentiation.To develop and validate a sensitive point-of-care test for differential molecular diagnosis based on ribosomal RNA (rRNA) detection.To strengthen research ...
New mechanisms of drug resistance in malaria parasites: a molecular, epidemiological and social study Instituut voor Tropische Geneeskunde
Estimating the effective reproductive rate of M. Tuberculosis from changes in molecular clustering rates, to measure the impact of public health interventions on TB transmission Instituut voor Tropische Geneeskunde
The major aim of the present proposal is to understand whether ECF has the ability to reduce transmission of TB in the intervention group when compared to the control group. To achieve this, the following objectives are defined:
Compare the proportion of TB-due-to-recent-transmission in intervention and control arms of a Cluster Randomized Trial on the impact of Enhanced Case Findinga) Genotype isolates ...
Molecular adaptation of the tsetse fly transmited African trypanosome to the intradermal micro-environment in the mammalian host Instituut voor Tropische Geneeskunde
Identificatie van de moleculaire mechanismen van non-respons op behandelingen, terugvallen en remissie bij auto-immuunziekten, inflammatoire en allergische aandoeningen KU Leuven
3TR is a transdisciplinary consortium made of experts in all areas of medicine, basic sciences and bioinformatics from academic institutions, SMEs, and 8 major pharmaceutical companies, teamed to study a fundamental issue in medicine: the mechanisms of response and non-response to therapies, the major aim of 3TR, both within single disease entities and across diseases, where molecular stratification may identify shared disease taxonomies. The ...
To enhance the research capacity and evidence based medical practice in tropical and poverty related diseases in Ethiopia Instituut voor Tropische Geneeskunde
Building on the needs jointly identified during FA3-III, in the present proposal, we ...
Dynamische modellering van menselijke progressieve longfibrose in een menselijke long chip KU Leuven
Mijn onderzoeksdoel is het ontwikkelen van geavanceerde, door patiënten afgeleide complexe celmodellen van interstitiële longziekten met progressieve fibrose (PF-ILD), die geschikt zijn voor precisiegeneeskunde en implementatie binnen initiatieven voor het ontdekken van geneesmiddelen voor een betere anti-fibrotische of ziekte het wijzigen van medicijnen. PF-ILD heeft een fatale afloop, met longtransplantatie als enige therapeutische optie. ...
Translationele SYStemics: gepersonaliseerde geneeskunde op het raakvlak van translationeel onderzoek en systeemgeneeskunde KU Leuven
TranSYS will recruit 15 ESRs to highly skilled jobs in the new area of Systems Health developing tools and approaches to exploit large and complex datasets, to advance Precision (Personalised) Medicine in several disease areas. The training programme and experience of different international research environments cuts across traditional data and life sciences silos. The emphasis on translational research will support new collaborations ...